儿童精神药理学中的精神药理学基因组学。

Psychiatric pharmacogenomics in pediatric psychopharmacology.

机构信息

Division of Child and Adolescent Psychiatry, Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Child Adolesc Psychiatr Clin N Am. 2012 Oct;21(4):773-88. doi: 10.1016/j.chc.2012.07.001.

DOI:10.1016/j.chc.2012.07.001

PMID:23040901

Abstract

This article provides an overview of where psychiatric pharmacogenomic testing stands as an emerging clinical tool in modern psychotropic prescribing practice, specifically in the pediatric population. This practical discussion is organized around the state of psychiatric pharmacogenomics research when choosing psychopharmacologic interventions in the most commonly encountered mental illnesses in youth. As with the rest of the topics on psychopharmacology for children and adolescents in this publication, a clinical vignette is presented, this one highlighting a clinical case of a 16 year old genotyped during hospitalization for recalcitrant depression.

摘要

本文概述了精神药理学基因组检测作为一种新兴的临床工具在现代精神药物处方实践中的地位，特别是在儿科人群中。本实用讨论围绕着在儿童和青少年精神药理学中最常见的精神疾病选择精神药物干预时精神药理学基因组学研究的现状。就本出版物中关于儿童和青少年精神药理学的其他主题一样，本文呈现了一个临床病例，该病例突出了一个在住院治疗难治性抑郁症期间进行基因分型的 16 岁患者的临床案例。