Goldfarb D A, Lorig R, Zelch M, Patrone P, Bukowski R M, Pontes J E
Department of Urology, Cleveland Clinic Foundation, Ohio.
J Urol. 1990 Mar;143(3):574-7. doi: 10.1016/s0022-5347(17)40024-3.
This case illustrates the difficulties that sometimes occur in the evaluation of patients with a nonfunctioning kidney. Because of the clinical presentation, suggestive of renal cell carcinoma, no urinary cytology study was obtained from the affected kidney. This study certainly would have led to the correct diagnosis. Despite this fact, the operative management would not have changed except for complete removal of the ureter. In our case we elected to follow the distal ureter by ureteral washings and ureteroscopy during follow-up cystoscopy studies to preclude a further operation. Although no data are available on the role of adjuvant therapy in these patients, because of the poor prognosis associated with such extensive disease we gave our patient 2 courses of M-VAC in an attempt to prevent progression of the disease.
该病例说明了在评估无功能肾患者时有时会出现的困难。由于临床表现提示肾细胞癌,未对患肾进行尿细胞学检查。这项检查肯定会得出正确诊断。尽管如此,除了完全切除输尿管外,手术管理不会有其他改变。在我们的病例中,我们选择在后续膀胱镜检查期间通过输尿管冲洗和输尿管镜检查追踪输尿管远端,以避免进一步手术。虽然尚无关于辅助治疗在这些患者中作用的数据,但由于这种广泛疾病的预后较差,我们给予患者两疗程的M-VAC方案,试图防止疾病进展。