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研究鼓励纤维肌痛患者运动(REEF):使用动机性访谈,随机对照试验的结果。

Research to encourage exercise for fibromyalgia (REEF): use of motivational interviewing, outcomes from a randomized-controlled trial.

机构信息

Department of Medicine, Division of Rheumatology, Indiana University, Indianapolis, IN 46202, USA.

出版信息

Clin J Pain. 2013 Apr;29(4):296-304. doi: 10.1097/AJP.0b013e318254ac76.

Abstract

OBJECTIVES

Regular exercise is associated with important benefits in patients with fibromyalgia (FM). Unfortunately, long-term maintenance of exercise after a structured program is rare. The present study tested the efficacy of Motivational Interviewing (MI) to promote exercise and improve symptoms in patients with FM.

METHODS

A total of 216 patients with FM were randomized to 6 MI sessions (n=107) or an equal number of FM self-management lessons (education control/EC, n=109). Co-primary endpoints were an increase of 30 minutes in moderate-vigorous physical activity and improvement in the Fibromyalgia Impact Questionnaire (FIQ)-Physical Impairment score, assessed at pretreatment, posttreatment, and 3-month and 6-month follow-up. Secondary outcomes included clinically meaningful improvements in FIQ score, pain severity ratings, and a 6-minute walk test.

RESULTS

There were no significant treatment group differences in either co-primary endpoint at 6-month follow-up. However, more MI participants than controls exhibited meaningful improvements in FIQ score at 6-month follow-up (62.9% vs. 49.5%, P=0.06). Compared with EC participants, MI participants also displayed a larger increment in their 6-minute walk test (43.9 vs. 24.8 m, P=0.03). In addition, MI was superior to EC in increasing the number of hours of physical activity immediately postintervention and in reducing pain severity both immediately after the intervention and at 3-month follow-up.

CONCLUSIONS

Despite a lack of benefits on long-term outcome, MI seems to have short-term benefits with respect to self-report physical activity and clinical outcomes. This is the first study in FM that explicitly addresses exercise maintenance as a primary aim.

摘要

目的

规律运动与纤维肌痛(FM)患者的重要获益相关。遗憾的是,在结构化方案后长期坚持运动的情况罕见。本研究旨在检验动机访谈(MI)在促进运动和改善 FM 患者症状方面的疗效。

方法

共 216 例 FM 患者随机分为 MI 组(n=107)或 FM 自我管理课程组(教育对照/EC,n=109),接受 6 次 MI 或相等数量的 FM 自我管理课程。主要结局为中-高强度体力活动增加 30 分钟,治疗前、治疗后、3 个月和 6 个月随访时的纤维肌痛影响问卷(FIQ)-躯体功能障碍评分改善。次要结局包括 FIQ 评分、疼痛严重程度评分和 6 分钟步行试验的临床意义改善。

结果

6 个月随访时,两组主要结局均无显著差异。然而,与 EC 组相比,更多的 MI 组患者在 6 个月随访时 FIQ 评分有显著改善(62.9% vs. 49.5%,P=0.06)。与 EC 组相比,MI 组患者的 6 分钟步行试验增量更大(43.9 vs. 24.8 m,P=0.03)。此外,与 EC 组相比,MI 组即刻干预后体力活动时间增加,干预后即刻和 3 个月随访时疼痛严重程度降低。

结论

尽管长期结局无获益,但 MI 似乎具有短期获益,体现在自我报告的体力活动和临床结局方面。这是首个明确将运动维持作为主要目标的 FM 研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c44c/3541460/af255c6ff5b4/nihms369232f1.jpg

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