Yap Kenneth, Campbell Patrina, Cherk Martin, McGrath Catherine, Kalff Victor
Department of Nuclear Medicine, The Alfred Hospital, Melbourne, Victoria, Australia.
J Med Imaging Radiat Oncol. 2012 Oct;56(5):525-31. doi: 10.1111/j.1754-9485.2012.02438.x. Epub 2012 Sep 7.
There is limited data on the effect of posture on LVEF. The study aim was to determine any difference in LVEF using gated cardiac blood pool scanning (GCBPS) and Tl-201 gated myocardial perfusion scanning (MPS) in prone or supine positions.
In 50 patients undergoing evaluation for varying heart conditions, automated LVEF, end diastolic volume (EDV), end systolic volume (ESV) measurements were obtained at rest during gated MPS on Discovery NM 530c (GE Healthcare). In another 50 patients, semi-automated LVEF measurements were obtained using GCBPS on dual-headed gamma cameras. Average heart rate (HR) was recorded. Differences between prone and supine LVEF, HR, EDV and ESV were compared using paired two-tailed t-tests (P < 0.05 considered significant). Pearson's correlation, difference plots, mean, standard deviation and 95% confidence interval of the differences were also derived to analyse LVEF results.
Using GCPBS or MPS, no significant difference in LVEF or LV volumes (from gated MPS) was demonstrated between postures. Increased HR was noted in prone positioning.
Posture did not affect measured LVEF or LV volumes. However HR was higher on prone imaging.
关于姿势对左心室射血分数（LVEF）影响的数据有限。本研究旨在通过门控心血池扫描（GCBPS）和铊 - 201门控心肌灌注扫描（MPS）来确定俯卧位或仰卧位时LVEF的差异。
对50例因各种心脏疾病接受评估的患者，在Discovery NM 530c（通用电气医疗集团）上进行门控MPS检查时，于静息状态下自动测量LVEF、舒张末期容积（EDV）和收缩末期容积（ESV）。对另外50例患者，使用双头γ相机通过GCBPS进行半自动LVEF测量。记录平均心率（HR）。采用配对双尾t检验比较俯卧位和仰卧位LVEF、HR、EDV和ESV之间的差异（P < 0.05认为有统计学意义）。还推导了Pearson相关性、差异图、差异的均值、标准差和95%置信区间，以分析LVEF结果。
使用GCPBS或MPS，不同姿势之间LVEF或左心室容积（来自门控MPS）无显著差异。俯卧位时HR升高。
姿势不影响所测LVEF或左心室容积。然而，俯卧位成像时HR较高。
