Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
PLoS One. 2012;7(9):e46274. doi: 10.1371/journal.pone.0046274. Epub 2012 Sep 26.
Shifting polio eradication strategies may have generated fear and "resistance" to the eradication program in Aligarh, India during the summer of 2009. Participant observation and formal interviews with 107 people from May to August 2009 indicated that the intensified frequency of vaccination was correlated with patients' doubt in the efficacy of the vaccine. This doubt was exacerbated in a few cases as families were uninformed of the use of monovalent mOPV1, while P3 cases continued to occur. Many families had also come to believe that their children had been adversely affected by OPV after being told the vaccine carried no risk. Though polio is now largely eradicated in India, with only a single case in 2011, greater transparency about changes with vaccination policy may need to be considered to build trust with the public in future eradication programs.
2009 年夏季，印度阿拉哈巴德改变脊髓灰质炎根除策略，可能引发民众对根除计划的恐惧和“抵触”。2009 年 5 月至 8 月，通过对 107 人进行参与性观察和正式访谈发现，疫苗接种频率的增加与患者对疫苗效果的怀疑有关。在少数情况下，由于未告知使用单价 mOPV1，而 P3 病例仍在继续发生，家庭对此表示怀疑。许多家庭还认为，在被告知疫苗没有风险后，他们的孩子接种 OPV 后受到了不良影响。尽管印度目前已基本根除脊髓灰质炎，2011 年仅出现一例病例，但未来根除计划可能需要考虑提高疫苗接种政策变化的透明度，以赢得公众的信任。
