Schmidt Kirsten Tryde, Andersen Anders Nyboe, Loft Anne, Ernst Erik, Andersen Claus Yding
Fertilitetsklinikken, Rigshospitalet, Blegdamsvej 9, Copenhagen.
Ugeskr Laeger. 2012 Oct 8;174(41):2455-9.
Patients with cancer are at risk of loss of gonadal function due to the cancer treatment. Chemo- and radiation therapy are known to induce gonadal failure in both men and women and especially treatment with alkylating agents and/or abdominal or testicular radiation therapy poses a high risk. Methods exist to preserve fertility and these should be discussed with and offered to the patient if necessary and possible. For men, cryopreservation of semen is simple, non-invasive and low-cost. For women, cryopreservation of oocytes, embryos or ovarian tissue is an option in order to preserve fertility.
癌症患者因癌症治疗有性腺功能丧失的风险。已知化疗和放疗会导致男性和女性性腺功能衰竭，尤其是使用烷化剂和/或腹部或睾丸放疗的治疗风险很高。存在保存生育能力的方法，如有必要且可行，应与患者讨论并提供这些方法。对于男性，精液冷冻保存简单、无创且成本低。对于女性，卵母细胞、胚胎或卵巢组织冷冻保存是一种保存生育能力的选择。
