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接受恶性肿瘤治疗的儿童和青年的生育力保存

Fertility preservation in children and young adults undergoing treatment for malignancy.

作者信息

Al-Fozan Haya M, Tulandi Togas

机构信息

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia.

出版信息

Saudi Med J. 2004 Feb;25(2):141-4.

PMID:14968206
Abstract

Advances in cancer therapy have improved the long-term survival of young patients suffering from malignancies. However, the adverse effects of the treatment are sterility and loss of gonadal function especially in females. Preservation of fertility in males by sperm freezing is more practical and already established. For young women undergoing cancer treatment, the availability of preserving the gonadal function and fertility has just begun. Today, we can cryopreserve the oocytes, the embryos or the ovarian tissue and in those undergoing pelvic irradiation, laparoscopic lateral ovarian suspension can be considered. Because women with non-gynecological malignancies seek advice from a general surgeon or a medical oncologist, increasing the awareness of the physicians and general public is recommended.

摘要

癌症治疗的进展提高了患有恶性肿瘤的年轻患者的长期生存率。然而,治疗的副作用是不育和性腺功能丧失,尤其是在女性中。通过冷冻精子来保存男性生育能力更为实际且已得到确立。对于接受癌症治疗的年轻女性来说,保存性腺功能和生育能力的方法才刚刚起步。如今,我们可以冷冻卵母细胞、胚胎或卵巢组织,对于接受盆腔放疗的患者,可以考虑进行腹腔镜下卵巢侧方悬吊术。由于患有非妇科恶性肿瘤的女性会向普通外科医生或肿瘤内科医生咨询,因此建议提高医生和公众的认识。

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