Park Sanghui, Ko Young Hyeh
Department of Pathology, Ewha Womans University School of Medicine, Seoul, Korea.
Tumori. 2012 Jul-Aug;98(4):e111-4. doi: 10.1177/030089161209800424.
The neural adhesion molecule CD56 is normally expressed on natural killer cells and subsets of T cells and is commonly found in hematolymphoid neoplasms. Expression of CD56 is very rare in B-cell lymphoma and most reported CD56-positive cases were diffuse large B-cell lymphomas. Cases of CD56-positive mantle cell lymphoma (MCL) have not previously been described in the literature. We present a case of CD56-positive MCL. To the best of our knowledge, this is the first case report of MCL expressing CD56.
神经黏附分子CD56通常表达于自然杀伤细胞和T细胞亚群，在血液淋巴系统肿瘤中也较为常见。CD56在B细胞淋巴瘤中的表达非常罕见，大多数报道的CD56阳性病例为弥漫性大B细胞淋巴瘤。CD56阳性套细胞淋巴瘤（MCL）病例此前在文献中尚未见报道。我们报告一例CD56阳性MCL病例。据我们所知，这是首例关于表达CD56的MCL的病例报告。
