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青少年双相情感障碍与自杀:对过去 10 年文献的回顾。

Juvenile bipolar disorder and suicidality: a review of the last 10 years of literature.

机构信息

Département de psychologie, Université du Québec à Montréal, C.P. 8888, succursale Centre-ville, Montreal, QC, H3C 3P8, Canada.

出版信息

Eur Child Adolesc Psychiatry. 2013 Mar;22(3):139-51. doi: 10.1007/s00787-012-0328-z. Epub 2012 Oct 7.

Abstract

Although children and adolescents with bipolar disorder (BD) are at elevated risk for suicide, little research to date has been conducted on suicidality in this population. The purpose of this descriptive review of the past 10 years of scientific literature on suicidality in youths with BD was to identify the risk and protective factors associated with this phenomenon, and to discuss the implications for research and clinical practice. Searches on Medline and PsycINFO databases for the period from early 2002 to mid-2012 yielded 16 relevant articles, which were subsequently explored using an analysis grid. Note that the authors employed a consensus analysis approach at all stages of the review. Four primary categories of risk factors for suicidality in youths with BD were identified: demographic (age and gender), clinical (depression, mixed state or mixed features specifier, mania, anxiety disorders, psychotic symptoms, and substance abuse), psychological (cyclothymic temperament, hopelessness, poor anger management, low self-esteem, external locus of control, impulsivity and aggressiveness, previous suicide attempts, and history of suicide ideation, non-suicidal self-injurious behaviors and past psychiatric hospitalization), and family/social (family history of attempted suicide, family history of depression, low quality of life, poor family functioning, stressful life events, physical/sexual abuse, and social withdrawal). Youths with BD who experienced more complex symptomatic profiles were at greater risk of suicidality. Few protective factors associated with suicidality have been studied among youths with BD. One protective factor was found in this descriptive literature review: the positive effects of dialectical behavior therapy. This article allows a better appreciation of the risk and protective factors associated with suicidality among youth with BD. Greater awareness of risk factors is the first step in suicide prevention.

摘要

尽管患有双相情感障碍 (BD) 的儿童和青少年自杀风险较高,但迄今为止,针对该人群自杀问题的研究甚少。本描述性文献回顾旨在回顾过去 10 年关于 BD 青少年自杀问题的科学文献,以确定与这一现象相关的风险和保护因素,并讨论其对研究和临床实践的意义。通过 Medline 和 PsycINFO 数据库对 2002 年初至 2012 年年中期间的文献进行检索,共获得 16 篇相关文章,随后使用分析网格对这些文章进行了探讨。请注意,作者在审查的所有阶段都采用了共识分析方法。确定了与 BD 青少年自杀相关的四大类风险因素:人口统计学因素(年龄和性别)、临床因素(抑郁、混合状态或混合特征指定、躁狂、焦虑障碍、精神病症状和物质滥用)、心理因素(环性气质、绝望、愤怒管理不善、自尊心低、外部控制、冲动和攻击性、既往自杀企图和自杀意念史、非自杀性自伤行为和既往精神科住院治疗)以及家庭/社会因素(自杀未遂家族史、抑郁家族史、生活质量低、家庭功能差、生活压力事件、身体/性虐待和社会退缩)。经历更复杂症状谱的 BD 青少年自杀风险更高。在 BD 青少年中,与自杀相关的保护因素研究甚少。本描述性文献回顾发现了一个保护因素:辩证行为疗法的积极作用。本文使我们更好地了解与 BD 青少年自杀相关的风险和保护因素。提高对风险因素的认识是预防自杀的第一步。

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