Mises J, Gabersek V, Lacombe J, Hirsch J F, Pierre-Kahn A, Zouaoui A, Barritault L, Rimbert J, N'Geh R
Rev Electroencephalogr Neurophysiol Clin. 1979 Jul-Sep;9(3):228-35. doi: 10.1016/s0370-4475(79)80003-9.
This study was carried with the intention of explaining the causes of modifications in intracranial pressure (ICP) during paradoxical sleep (PS) in normal and hydrocephalic infants, and establishing relationships between these modifications and cerebral blood volume (CBV). All tests (conventional sleep polygraphy, ICP measured by a transducer on the fontanel, CBV measured by isotopic labelling of red blood cells in vivo) were carried out without use of surgical procedures. During paradoxical sleep there was a sustained wave of increased intracranial pressure lasting from 10 to 20 minutes, as well as phase-type variations lasting no longer than 1 minute. Increased ICP was also observed in the normal subjects. Recordings show that there is well-defined correlation between the sustained wave of high intracranial pressure and an increase in CBV.
本研究旨在解释正常婴儿和脑积水婴儿在异相睡眠（PS）期间颅内压（ICP）变化的原因，并建立这些变化与脑血容量（CBV）之间的关系。所有测试（传统睡眠多导记录法、通过前囟门上的传感器测量ICP、通过体内红细胞同位素标记测量CBV）均在不进行外科手术的情况下进行。在异相睡眠期间，存在持续10至20分钟的颅内压升高波，以及持续时间不超过1分钟的相位型变化。在正常受试者中也观察到ICP升高。记录显示，高颅内压持续波与CBV增加之间存在明确的相关性。
