Kapfhammer Hans-Peter, Lange Peter
Universitätsklinik für Psychiatrie, Medizinische Universität Graz, Auenbruggerplatz 31, 8036, Graz, Österreich,
Neuropsychiatr. 2012;26(3):129-38. doi: 10.1007/s40211-012-0023-9.
A sample of patients with a puerperal psychosis of an early manifestation is investigated in respect of special risks of suicide and infanticide.
During a 20-year period 96 patients who had been fallen ill with a puerperal psychosis within four weeks after delivery were admitted to a psychiatric university hospital. Patients with an acute exacerbation of a known schizophrenic disorder were excluded. In a subgroup of 37 patients states of a previous (affective, bipolar affective) psychotic illness were recorded already before the puerperal index episode, in a subgroup of 59 patients puerperal psychosis was the first manifestation of a psychotic illness. Suicide- and infanticide-relevant psychopathological symptoms were analysed (suicidal ideas/behaviour before/during inpatient treatment, general disorganized aggression, psychotic anxieties related to baby, infanticidal obsessions, aggressive ideas/behaviour towards baby, neglect, infanticidal impulses).
Puerperal psychoses were distributed to the diagnostic categories of psychotic depressive disorder, bipolar affective disorder, and schizoaffective disorder. Six patients died due to suicide, tragically already some few days till weeks after discharge from psychiatric hospital, despite a pronounced or even complete remission of puerperal psychotic symptoms at the time of discharge. Three patients committed an extended suicide attempt that resulted in two infanticides. All isolated and extended suicides were committed in a state of depressive mood and presumably synthymic delusion.
Suicidal ideas and behaviour play a major role in patients with puerperal psychosis before and during inpatient treatment. An increased risk for mothers and babies may persist, however, even after a seemingly good symptomatic remission. Besides the clinical challenge of general prevention of puerperal psychosis the request of adequate models of inpatient treatment, carefully prepared discharge, close afterdischarge follow up, and continuous outpatient care have to be stressed.
对一组具有早期表现的产褥期精神病患者样本进行自杀和杀婴特殊风险方面的调查。
在20年期间,96名在分娩后四周内患产褥期精神病的患者被收治到一家大学精神病医院。已知精神分裂症障碍急性加重的患者被排除。在一个37名患者的亚组中,在产褥期指数发作之前就已记录有先前(情感性、双相情感性)精神病性疾病状态;在一个59名患者的亚组中,产褥期精神病是精神病性疾病的首发表现。分析了与自杀和杀婴相关的精神病理症状(住院治疗前/期间的自杀观念/行为、一般性混乱攻击行为、与婴儿相关的精神病性焦虑、杀婴妄想、对婴儿的攻击观念/行为、忽视、杀婴冲动)。
产褥期精神病分布于精神病性抑郁障碍、双相情感障碍和分裂情感障碍的诊断类别中。6名患者死于自杀,悲惨的是,尽管出院时产褥期精神病症状明显缓解甚至完全缓解,但仍在出院后几天至几周内发生。3名患者进行了扩大的自杀企图,导致2起杀婴事件。所有单独和扩大的自杀行为均在抑郁情绪状态下实施,可能伴有心境协调妄想。
自杀观念和行为在产褥期精神病患者住院治疗前和治疗期间起主要作用。然而,即使在症状看似良好缓解后,母亲和婴儿的风险可能仍然增加。除了产褥期精神病的一般预防这一临床挑战外,还必须强调适当的住院治疗模式、精心准备的出院、出院后密切随访以及持续的门诊护理的要求。