Friend W G
University of Washington, School of Medicine, Seattle, Washington.
Am Fam Physician. 1990 Mar;41(3):891-4.
Sulindac causes both regression and suppression of colorectal polyps in patients with Gardner's syndrome and familial polyposis coli. Three patients with Gardner's syndrome and multiple colonic polyps had complete regression of polyps after two to three months of sulindac therapy. The implication that sulindac may prevent colorectal cancer and prophylactic surgery in patients with hereditary polyps of the colon is intriguing but has not yet been substantiated.
舒林酸可使加德纳综合征和家族性结肠息肉病患者的结肠息肉消退并受到抑制。3例患有加德纳综合征和多发性结肠息肉的患者在接受舒林酸治疗两到三个月后息肉完全消退。舒林酸可能预防遗传性结肠息肉患者患结直肠癌及避免进行预防性手术这一观点很有意思，但尚未得到证实。
