Waddell W R, Ganser G F, Cerise E J, Loughry R W
Department of Surgery, University of Colorado, Denver.
Am J Surg. 1989 Jan;157(1):175-9. doi: 10.1016/0002-9610(89)90442-x.
The effect of sulindac, a nonsteroid antiinflammatory drug, on colon polyposis has been evaluated in seven patients after subtotal colectomy and ileoproctostomy and in four patients with intact colons. The patients all had Gardner's syndrome or familial polyposis coli. All polyps were eliminated, except for a few that arose in the rectal mucosa and the anal canal. No cancers developed in these patients on follow-up.
已对7例接受结肠次全切除术和回肠直肠吻合术的患者以及4例结肠完整的患者评估了非甾体抗炎药舒林酸对结肠息肉病的影响。所有患者均患有加德纳综合征或家族性结肠息肉病。除直肠黏膜和肛管出现的少数息肉外，所有息肉均被清除。这些患者在随访中均未发生癌症。
