Zhuo Naiqiang, Wan Yongxian, Lu Xiaobo, Zhang Zhongjie, Tan Meiyun, Chen Ge
Department of Orthopedics, Affiliated Hospital of Luzhou Medical College, Luzhou Sichuan 646000, PR China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2012 Sep;26(9):1041-4.
To evaluate the effectiveness of comprehensive management for early stage avascular necrosis of the femoral head (ANFH) by arthroscopic minimally invasive surgery by comparing with closed core decompression.
Between January 2007 and March 2010, 28 patients (33 hips) with early stage ANFH were treated with the procedure of arthroscopic core decompression combined with autogenous cancellous bone graft and bone morphogenetic protein (BMP) in 18 cases (21 hips, trial group) or with simple closed core decompression in 10 cases (12 hips, control group). No significant difference was found in gender, age, disease duration, etiology, and staging between 2 groups (P > 0.05).
Incision healed primarily in all patients, and no infection occurred. All patients were followed up 2.5 years on average (range, 1-3 years). Pain relief and improvement of hip function were obtained in all patients at 6 months after operation. At last follow-up, the Harris scores were 85.67 +/- 4.78 in trial group and 81.33 +/- 7.03 in control group, showing significant difference between 2 groups (t = -2.10, P = 0.04). Collapse of the femoral head was observed in 1 hip (Ficat stage II) of trial group, and in 2 hips (Ficat stage I) and 2 hips (Ficat stage II) of control group; hip arthroplasty was performed. Significant difference in total effective rate was found between trial group and control group (95.24% vs. 66.67%; chi2 = 4.85, P = 0.03).
Arthroscopic core decompression combined with autogenous cancellous bone graft and BMP is more effective than traditional closed core decompression for treatment of early stage ANFH in pain relief, improvement of hip function, slowing-down the process of femoral head necrosis, reduction of hip joint replacement by accurate location of the lesions, and thoroughly debridement of necrotic bone.
通过与髓芯减压术对比,评估关节镜下微创手术综合治疗早期股骨头缺血性坏死(ANFH)的疗效。
2007年1月至2010年3月,28例(33髋)早期ANFH患者,其中18例(21髋)采用关节镜下髓芯减压联合自体松质骨移植及骨形态发生蛋白(BMP)治疗(试验组),10例(12髋)采用单纯髓芯减压治疗(对照组)。两组患者在性别、年龄、病程、病因及分期方面差异无统计学意义(P > 0.05)。
所有患者切口均一期愈合,无感染发生。所有患者平均随访2.5年(范围1 - 3年)。术后6个月所有患者疼痛均缓解,髋关节功能改善。末次随访时,试验组Harris评分为85.67 ± 4.78,对照组为81.33 ± 7.03,两组差异有统计学意义(t = -2.10,P = 0.04)。试验组1髋(Ficat II期)、对照组2髋(Ficat I期)和2髋(Ficat II期)出现股骨头塌陷,行髋关节置换术。试验组与对照组总有效率差异有统计学意义(95.24% vs. 66.67%;χ² = 4.85,P = 0.03)。
关节镜下髓芯减压联合自体松质骨移植及BMP治疗早期ANFH在缓解疼痛、改善髋关节功能、延缓股骨头坏死进程、减少髋关节置换方面比传统髓芯减压更有效,能准确定位病变并彻底清除坏死骨。