Waterman S H, Juarez G, Carr S J, Kilman L
Acute Communicable Disease Control Unit, Los Angeles County Department of Health Services, CA 90012.
Am J Public Health. 1990 Mar;80(3):286-9. doi: 10.2105/ajph.80.3.286.
In 1987 two Los Angeles County (California) hospitals reported four Latino patients with serious Salmonella arizona (Salmonella subgroup 3) infections who gave a medical history of taking rattlesnake capsules prior to illness. Capsules supplied by the patients or household members grew Salmonella arizona. We reviewed surveillance data for this Salmonella species and conducted a case-control study to determine the magnitude of this public health problem. Eighteen (82 percent) of the 22 Latino cases in 1986 and 1987 who were questioned reported ingesting snake capsules compared to two (8 percent) of 24 matched Latino controls with non-subgroup 3 salmonellosis or shigellosis (matched pair odds ratio = 18.0, CI = 4.2, 76.3). An average of 18 cases per year of Salmonella arizona were reported in the county between 1980 and 1987. In this investigation the majority of S. arizona cases reporting snake capsule ingestion had underlying illnesses such as acquired immunodeficiency syndrome (AIDS), diabetes, arthritis, cancer. The capsules were obtained primarily from Tijuana, Mexico and from Los Angeles, California pharmacies in Latino neighborhoods. Despite publicity and attempts to remove the capsules from sale in California, Salmonella arizona cases associated with snake-capsule ingestion continue to occur.
1987年,加利福尼亚州洛杉矶县的两家医院报告了4名感染亚利桑那沙门氏菌(沙门氏菌3亚群)的拉丁裔患者,他们在患病前有服用响尾蛇胶囊的病史。患者或其家庭成员提供的胶囊培养出了亚利桑那沙门氏菌。我们查阅了该沙门氏菌的监测数据,并开展了一项病例对照研究,以确定这一公共卫生问题的严重程度。在1986年和1987年接受询问的22例拉丁裔病例中,有18例(82%)报告摄入了蛇胶囊,而24例匹配的患有非3亚群沙门氏菌病或志贺氏菌病的拉丁裔对照者中只有2例(8%)报告摄入了蛇胶囊(配对比值比=18.0,可信区间=4.2,76.3)。1980年至1987年间,该县每年平均报告18例亚利桑那沙门氏菌病例。在本次调查中,大多数报告摄入蛇胶囊的亚利桑那沙门氏菌病例都有潜在疾病,如获得性免疫缺陷综合征(艾滋病)、糖尿病、关节炎、癌症。这些胶囊主要从墨西哥蒂华纳以及加利福尼亚州洛杉矶拉丁裔社区的药店购得。尽管进行了宣传并试图在加利福尼亚州禁止销售这些胶囊,但与摄入蛇胶囊相关的亚利桑那沙门氏菌病例仍在继续发生。