Learch Thomas J, Sakamoto Brian, Ling Amy C, Donovan Suzanne M
Radiology, S. Mark Taper Foundation Imaging Center, Cedars-Sinai Medical Center, 8700 Beverly Blvd., Suite M-335, Los Angeles, CA 90048, USA.
Emerg Radiol. 2009 Mar;16(2):147-50. doi: 10.1007/s10140-008-0713-6. Epub 2008 May 8.
Each year, 1.4 million people in the United States are infected with Salmonella (Beneson et al. [23] Am J Med, 110:60-63, 2001). The most common clinical presentation of Salmonella infection is gastroenteritis which is usually self-limited, lasting between one to four days (Black et al. [24] N Engl J Med, 261:811-816, 1960). Although most infections are mild-to-moderate, serious disease, and death does occur (Voetsch et al. [25] CID, 38:S127-S132, 2004). A rare but increasing number of patients present with Salmonellosis spondylodiscitis resulting from contiguous spread of infection from the adjacent abdominal aorta. Concurrent infection of these structures exacerbates morbidity, necessitating an elevated clinical suspicion in patients with appropriate risk factors, clinical signs and symptoms. Furthermore, an overall mortality rate of 67% makes mycotic abdominal aortic aneurysms highly lethal (Gonda et al. [26] Radiology, 168:343-346, 1988). Thus, early diagnosis is crucial, allowing for prompt antibiotic and surgical management. Laboratory and imaging tests obtained at the initial suspicion for infection of the spine and aorta facilitates diagnosis while minimizing or preventing more serious complications like paresis and aortic rupture. We present a patient with a mycotic abdominal aortic aneurysm infected with Salmonella enteritides that spread to the adjacent lumbar vertebra and left psoas muscle.
在美国,每年有140万人感染沙门氏菌(贝内森等人[23]《美国医学杂志》,110:60 - 63,2001年)。沙门氏菌感染最常见的临床表现是肠胃炎,通常为自限性,持续1至4天(布莱克等人[24]《新英格兰医学杂志》,261:811 - 816,1960年)。虽然大多数感染为轻至中度,但严重疾病甚至死亡确实会发生(沃奇等人[25]《感染性疾病临床诊治》,38:S127 - S132,2004年)。一种罕见但数量不断增加的患者表现为沙门氏菌性脊椎椎间盘炎,这是由相邻腹主动脉感染的连续扩散引起的。这些结构的并发感染会加重发病率,因此对于有适当风险因素、临床体征和症状的患者,临床怀疑度必须提高。此外,67%的总体死亡率使霉菌性腹主动脉瘤具有高度致死性(贡达等人[26]《放射学》杂志,168:343 - 346,1988年)。因此,早期诊断至关重要,以便能迅速进行抗生素和手术治疗。在最初怀疑脊柱和主动脉感染时进行的实验室和影像学检查有助于诊断,同时将诸如麻痹和主动脉破裂等更严重并发症的发生降至最低或预防其发生。我们报告一例患有霉菌性腹主动脉瘤的患者,该动脉瘤感染了肠炎沙门氏菌,并扩散至相邻的腰椎和左腰大肌。