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母乳中吸烟和不吸烟母亲的细胞因子谱。

Cytokine profile of mature milk from smoking and nonsmoking mothers.

机构信息

Department of Pediatrics, Pediatric Gastroenterology, Hepatology, and Nutrition, Medical University of Gdansk, Gdansk, Poland.

出版信息

J Pediatr Gastroenterol Nutr. 2013 Apr;56(4):382-4. doi: 10.1097/MPG.0b013e318275f95c.

DOI:10.1097/MPG.0b013e318275f95c
PMID:23059645
Abstract

We verified whether smoking during lactation influences breast milk cytokine (interleukin [IL]-1α, IL-1β, IL-6, IL-8, IL-10, and tumor necrosis factor-α) levels 30 to 32 days after delivery. The study group comprised 24 postpartum women who declared smoking >5 cigarettes per day. The control group included 45 nonsmoking postpartum women. Compared with nonsmoking women, smokers were characterized by significantly higher breast milk concentrations of IL-1α (P = 0.04), whereas no significant intergroup differences were observed in terms of remaining analyzed cytokines. Moreover, both groups were characterized by a similar fraction of women with detectable cytokine levels.

摘要

我们验证了哺乳期吸烟是否会影响产后 30-32 天的母乳细胞因子(白细胞介素[IL]-1α、IL-1β、IL-6、IL-8、IL-10 和肿瘤坏死因子-α)水平。研究组包括 24 名每天吸烟超过 5 支的产后妇女。对照组包括 45 名不吸烟的产后妇女。与不吸烟的妇女相比,吸烟者的母乳中白细胞介素-1α(IL-1α)的浓度明显更高(P=0.04),而在其余分析的细胞因子方面,两组间没有显著差异。此外,两组具有可检测细胞因子水平的妇女比例相似。

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