Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Ludwig-Maximilians-University Munich, and Department of Paediatrics, Hospital Dritter Orden, Germany.
J Psychosom Res. 2012 Nov;73(5):369-74. doi: 10.1016/j.jpsychores.2012.08.016. Epub 2012 Oct 1.
This is the first study to validate and to compare the Children's Depression Inventory (CDI) and its short version (CDI:S) as screening tools for medically ill children.
A sample of 406 pediatric hospital patients, aged 9 to 12 years (56.2% male, 77.1% inpatients), completed the German CDI. Criterion validity of the 26-item CDI and the 10-item CDI:S was calculated by receiver operating characteristic (ROC) curves. DSM-IV diagnoses of depression based on the structured diagnostic interview for mental disorders in children and adolescents (Kinder-DIPS) served as the reference standard. Areas under the ROC curves as well as sensitivities and specificities for the optimal cutoffs were compared for both versions.
Diagnoses of major or minor depression were established for 7.4% of the children. Areas under the curve for the 26-item CDI (87.7%) and the 10-item CDI:S (88.2%) were comparable. For the CDI, the cutoff≥12 yielded the best balance between sensitivity (83.3%) and specificity (82.7%). At the optimal cutoff≥3, the CDI:S resulted in a high sensitivity of 93.3% and a specificity of 70.7%. Thus, the CDI:S proved to be as sensitive as the CDI, but was less specific than the full-length version.
Both the CDI and the CDI:S are valid screening instruments for depression in medically ill children. The sensitive and brief CDI:S is a promising tool in time-pressed settings such as pediatric care, but has to be followed by a thorough diagnostic assessment to rule out false positive cases.
这是第一项验证并比较儿童抑郁量表(CDI)及其简短版(CDI:S)作为患有医学疾病的儿童筛查工具的研究。
一项针对 406 名 9 至 12 岁儿科住院患者(56.2%为男性,77.1%为住院患者)的样本完成了德国 CDI。使用接收器操作特征(ROC)曲线计算 26 项 CDI 和 10 项 CDI:S 的临界效度。基于儿童和青少年精神障碍结构化诊断访谈(Kinder-DIPS)的 DSM-IV 抑郁诊断作为参考标准。比较了两种版本的 ROC 曲线下面积以及最佳临界值的敏感性和特异性。
7.4%的儿童被诊断为重度或轻度抑郁症。26 项 CDI(87.7%)和 10 项 CDI:S(88.2%)的曲线下面积相当。对于 CDI,临界值≥12 可在敏感性(83.3%)和特异性(82.7%)之间取得最佳平衡。在最佳临界值≥3 时,CDI:S 的敏感性为 93.3%,特异性为 70.7%。因此,CDI:S 的敏感性与 CDI 相当,但特异性低于全长版本。
CDI 和 CDI:S 都是患有医学疾病的儿童抑郁的有效筛查工具。敏感而简短的 CDI:S 是儿科护理等时间紧迫环境中的有前途的工具,但需要进行彻底的诊断评估以排除假阳性病例。