Sanchez-Crespo Alejandro
Department of Nuclear Medicine, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Appl Radiat Isot. 2013 Jun;76:55-62. doi: 10.1016/j.apradiso.2012.06.034. Epub 2012 Aug 29.
This review article compares PET imaging performance with Gallium-68 ((68)Ga) and Fluorine-18 ((18)F). The literature on this topic is scarce; hence in order to complete the published data, Monte Carlo calculations, as well as phantom measurements, were carried out. The qualitative and quantitative differences between (68)Ga and (18)F imaging were evaluated in terms of spatial resolution, sensitivity, contrast and activity recovery coefficients for both human PET systems and small animal PET scanners. The clinical and pre-clinical implications of these differences are discussed.
这篇综述文章比较了镓-68（⁶⁸Ga）和氟-18（¹⁸F）的正电子发射断层显像（PET）成像性能。关于该主题的文献稀缺；因此，为了完善已发表的数据，进行了蒙特卡罗计算以及体模测量。针对人体PET系统和小动物PET扫描仪，从空间分辨率、灵敏度、对比度和活度恢复系数方面评估了⁶⁸Ga和¹⁸F成像之间的定性和定量差异。讨论了这些差异在临床和临床前方面的意义。
