Balysheva V I, Rakhimov A A, Khlebnikov V S, Sergeev V A
Vopr Virusol. 1979 Nov-Dec(6):606-10.
The physical stability of Teschen disease virus (TDV) was tested. It was found that 8 M urea at 37 degrees C and 0.5% Tween-20 for 1-2 hours destroyed TDV with formation of morphologically distinct subunits. The morphology of TDV virions and its subunits formed under the effect of urea and Tween-20 was studied. Sedimentation constant (120 S) and the polypeptide composition of TDV were determined. In TDV, major polypeptides (VP1 less than or equal to 4) and minor polypeptides (VP1m and VP2m) were found their molecular weights being 82,000, 67,000, 35,000, 30,000, 77,000, and 46,000 daltons respectively.
对泰申病病毒（TDV）的物理稳定性进行了测试。结果发现，37℃下8M尿素和0.5%吐温-20处理1至2小时会破坏TDV，并形成形态上明显不同的亚基。研究了尿素和吐温-20作用下TDV病毒粒子及其亚基的形态。测定了TDV的沉降常数（120S）和多肽组成。在TDV中，发现了主要多肽（VP1≤4）和次要多肽（VP1m和VP2m），其分子量分别为82,000、67,000、35,000、30,000、77,000和46,000道尔顿。
