Andreev G, Mluchkov Kh, Dimitrova D
Vutr Boles. 1979;18(6):81-8.
Scintigraphic and radiometric investigation with 99mTc-pyrophosphate was carried out on the sacro-iliac joints of 79 patients: 48 with positive form of Behterev disease, 26 -- with probable form of the disease, 2 -- with Reiter syndrome and 2 -- with rheumatoid arthritis. Scintigraphy was combined with radiometric investigation (determination of sacro-iliac -- sacral index) with a view to obtaining quantitative information about the degree of accumulation of pyrophosphate in sacro-iliac joints. The data from the scintigraphic and radiometric investigations were juxaposed to clinical laboratory and X-ray investigations. Forty of the patients examined were HLA-B27 positive and 38 of them-HLA-B27 negative. Sacro-iliac index, determined in 13 healthy subjects (26 sacro-iliac joints) was within the limits of 1.18 +/- 0.094. The average value of the index of the 78 patients examined was 1.41 +/- 0.20. The index, during the first and second X-ray stage was 1.43 +/- 0.13 and 1.45 +/- 0.19 resp. The values decreased to 1.39 +/- 0.18 during the third X-ray stage, whereas in the fourth stage with completely ankylosis of the joints, the index was 1.20 +/- 0.07, being close to that of the control group of healthy subjects.
对79例患者的骶髂关节进行了99mTc-焦磷酸盐闪烁扫描和放射性测量研究:48例为贝赫切特病阳性型,26例为可能型,2例为赖特综合征,2例为类风湿关节炎。为了获取有关焦磷酸盐在骶髂关节中积聚程度的定量信息,闪烁扫描与放射性测量研究(骶髂-骶骨指数测定)相结合。闪烁扫描和放射性测量研究的数据与临床实验室及X线检查结果并列分析。40例受检患者HLA-B27阳性,38例HLA-B27阴性。在13名健康受试者(26个骶髂关节)中测定的骶髂指数在1.18±0.094范围内。78例受检患者的指数平均值为1.41±0.20。在X线检查的第一和第二阶段,该指数分别为1.43±0.13和1.45±0.19。在X线检查的第三阶段,该值降至1.39±0.18,而在关节完全强直的第四阶段,指数为1.20±0.07,接近健康受试者对照组的值。