Department of Dermatology, Hospital de Santo António, Centro Hospitalar do Porto, Porto, Portugal.
J Eur Acad Dermatol Venereol. 2012 Nov;26 Suppl 6:14-5. doi: 10.1111/j.1468-3083.2012.04712.x.
A 9-month-old infant, with no family history of atopy, presenting with erythematous, itchy plaques, and sleep disturbance, was diagnosed with atopic eczema (AE). Previous treatment with topical hydrocortisone and emollients had little effect. The infant was treated nightly with methylprednisolone aceponate (MPA) 0.1% (Advantan(®)) cream, in addition to emollients and an oral antihistamine. After 1 week of once-daily MPA 0.1% treatment, followed by 1 week of alternate-day treatment with Advantan, significant improvements in AE symptoms and sleep were observed. The patient's caregiver reported overall treatment satisfaction and no side effects of Advantan. For this infant with newly diagnosed AE, Advantan improved symptoms and sleep quality in a safe and well-tolerated manner.
一位 9 个月大的婴儿，无特应性家族史，表现为红斑、瘙痒斑块和睡眠障碍，被诊断为特应性皮炎（AE）。之前使用外用氢化可的松和保湿剂治疗效果不佳。该婴儿每晚使用甲基泼尼松龙戊酸酯（MPA）0.1%（Advantan®）乳膏，此外还使用保湿剂和口服抗组胺药。在每天使用 MPA 0.1%治疗 1 周后，接着隔日用 Advantan 治疗 1 周，AE 症状和睡眠得到显著改善。患者的照顾者报告总体治疗满意度，且 Advantan 无不良反应。对于这位新诊断为 AE 的婴儿，Advantan 以安全且耐受良好的方式改善了症状和睡眠质量。
