Crippa P R, Viappiani C
Department of Physics, University of Parma, Italy.
Eur Biophys J. 1990;17(6):299-305. doi: 10.1007/BF00258378.
Photoacoustic measurements made at various chopping frequencies on dense acqueous melanin suspensions have revealed a significant dependence upon pH and redox state. It is shown that such behaviour, differing from the simple predictions of the Rosencwaig-Gersho theory, can be explained in terms of finite carrier diffusion and recombination times. The implications of these findings with respect to the amorphous semiconductor model proposed to describe the dynamic role of epidermal melanin are discussed. From the experimental data, values of physical parameters were calculated which allow a qualitative correlation between chemical states and electronic behaviour and, consequently, some aspects of the molecular biology of the melanosome, founded on a rigorous base.
在不同斩波频率下对致密水相黑色素悬浮液进行的光声测量表明，其对pH值和氧化还原状态有显著依赖性。结果表明，这种不同于罗森克韦格 - 格肖理论简单预测的行为，可以用有限的载流子扩散和复合时间来解释。讨论了这些发现对于提出的描述表皮黑色素动态作用的非晶半导体模型的意义。根据实验数据计算了物理参数值，这些值允许在化学状态和电子行为之间进行定性关联，从而在严格的基础上对黑素小体的分子生物学的某些方面进行关联。
