Identification of two human ferritin H genes on the short arm of chromosome 6.
作者信息
Dugast I J, Papadopoulos P, Zappone E, Jones C, Theriault K, Handelman G J, Benarous R, Drysdale J W
机构信息
Department of Biochemistry, Tufts University, Boston, Massachusetts 02111.
出版信息
Genomics. 1990 Feb;6(2):204-11. doi: 10.1016/0888-7543(90)90558-c.
PMID:2307464
Abstract
We have found by analyses of human-hamster hybrid cells that two human ferritin H genes lie near the locus of the iron storage disease idiopathic hemochromatosis on chromosome 6p. One of these genes was isolated and shown to be a processed pseudogene. Comparison of its sequence with those of other ferritin H pseudogenes indicates that they may be derived from a functional H gene other than that on chromosome 11.
摘要
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