Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam-si 463-707, South Korea.
Osteoporos Int. 2012 Dec;23(12):2897-900. doi: 10.1007/s00198-012-2172-x. Epub 2012 Oct 18.
We medicated teriparatide in three patients, who had a nonunion of the femur even after the initial surgical intervention. Teriparatide was administered for 3-9 months after a diagnosis of nonunion. A successful union was obtained in all three patients without further surgical intervention, and no adverse events related to the use of teriparatide were observed. Our report showed that teriparatide could be an alternative to surgical intervention in nonunion of the femur.
我们给 3 名股骨骨不连患者使用了特立帕肽进行治疗,这些患者在初次手术干预后仍存在骨不连。在诊断为骨不连后,这 3 名患者使用特立帕肽治疗 3-9 个月。所有 3 名患者均无需进一步手术干预而成功愈合,且未观察到与使用特立帕肽相关的不良反应。我们的报告表明,特立帕肽可能是股骨骨不连的一种替代手术干预方法。