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特立帕肽治疗青年成人Garden IV型股骨颈骨折内固定松动术后骨不连：1例报告

Treatment of postoperative non-union with internal fixation loosening of Garden IV femoral neck fracture with teriparatide in a young adult: A case report.

作者信息

Lai Lili, Li Yifan, Shen Miaoda, Wang Xuanwei, Zhong Cheng, Xu Sanzhong

机构信息

Department of Orthopedics, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

Front Surg. 2022 Nov 3;9:938595. doi: 10.3389/fsurg.2022.938595. eCollection 2022.

DOI:10.3389/fsurg.2022.938595
PMID:36406375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9669336/
Abstract

BACKGROUND

Postoperative non-union of femoral neck fracture often needs secondary operation. We report a case of a postoperative non-union of femoral neck fracture treated with teriparatide.

CASE PRESENTATION

A young male patient with Garden IV femoral neck fracture who showed no obvious signs of healing 3 months after percutaneous hollow nail fixation in which the fracture line was enlarged and the hollow nail was withdrawn. Bone non-union healed after 6 months of continuous subcutaneous injection of teriparatide at a dosage of 20 mg/day after the patient refused a secondary surgery. As far as we know, there have been no relevant reports on this type of fracture yet.

CONCLUSIONS

Teriparatide is expected to be beneficial in treating young patients with a displaced femoral neck fracture who have difficulty in healing from non-union and who are keen on avoiding secondary surgery.

摘要

背景

股骨颈骨折术后骨不连常需二次手术。我们报告一例应用特立帕肽治疗的股骨颈骨折术后骨不连病例。

病例介绍

一名年轻男性患者，Garden Ⅳ型股骨颈骨折，经皮空心钉固定术后3个月无明显愈合迹象，骨折线增宽，空心钉退出。患者拒绝二次手术后，每天皮下注射20毫克特立帕肽持续6个月，骨不连得以愈合。据我们所知，此类骨折尚无相关报道。

结论

特立帕肽有望用于治疗移位型股骨颈骨折的年轻患者，这些患者骨不连愈合困难且希望避免二次手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ee8/9669336/68537850aba0/fsurg-09-938595-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ee8/9669336/ac01bbd4c0a4/fsurg-09-938595-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ee8/9669336/94d44d497f4e/fsurg-09-938595-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ee8/9669336/68537850aba0/fsurg-09-938595-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ee8/9669336/ac01bbd4c0a4/fsurg-09-938595-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ee8/9669336/94d44d497f4e/fsurg-09-938595-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ee8/9669336/68537850aba0/fsurg-09-938595-g003.jpg

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