Lai Lili, Li Yifan, Shen Miaoda, Wang Xuanwei, Zhong Cheng, Xu Sanzhong
Department of Orthopedics, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Front Surg. 2022 Nov 3;9:938595. doi: 10.3389/fsurg.2022.938595. eCollection 2022.
Postoperative non-union of femoral neck fracture often needs secondary operation. We report a case of a postoperative non-union of femoral neck fracture treated with teriparatide.
A young male patient with Garden IV femoral neck fracture who showed no obvious signs of healing 3 months after percutaneous hollow nail fixation in which the fracture line was enlarged and the hollow nail was withdrawn. Bone non-union healed after 6 months of continuous subcutaneous injection of teriparatide at a dosage of 20 mg/day after the patient refused a secondary surgery. As far as we know, there have been no relevant reports on this type of fracture yet.
Teriparatide is expected to be beneficial in treating young patients with a displaced femoral neck fracture who have difficulty in healing from non-union and who are keen on avoiding secondary surgery.
股骨颈骨折术后骨不连常需二次手术。我们报告一例应用特立帕肽治疗的股骨颈骨折术后骨不连病例。
一名年轻男性患者,Garden Ⅳ型股骨颈骨折,经皮空心钉固定术后3个月无明显愈合迹象,骨折线增宽,空心钉退出。患者拒绝二次手术后,每天皮下注射20毫克特立帕肽持续6个月,骨不连得以愈合。据我们所知,此类骨折尚无相关报道。
特立帕肽有望用于治疗移位型股骨颈骨折的年轻患者,这些患者骨不连愈合困难且希望避免二次手术。