Jindal Rashmi, Jain Anshu, Mittal Ankur, Shirazi Nadia
Department of Dermatology, Himalayan Institute Hospital Trust, Dehradun, Uttaranchal, India.
BMJ Case Rep. 2012 Oct 12;2012:bcr2012006869. doi: 10.1136/bcr-2012-006869.
Sweet's syndrome is a neutrophilic inflammatory dermatosis presenting with sudden onset tender red to purple papules and nodules, fever and neutrophilia. Gastrointestinal and urinary tract infections, pregnancy, inflammatory bowel disease, drugs and malignancy are some of the known aetiological factors. Paraneoplastic Sweet's syndrome accounts for 15-20% cases and thus forms an important subset. At times its onset helps in suspecting an underlying malignancy, thus making timely intervention possible. In the present case report Sweet's syndrome was the presenting feature of gall bladder adenocarcinoma; an association that has been rarely reported before.
斯威特综合征是一种嗜中性粒细胞性炎症性皮肤病,表现为突发的、触痛的红色至紫色丘疹和结节、发热及嗜中性粒细胞增多。胃肠道和尿路感染、妊娠、炎症性肠病、药物及恶性肿瘤是一些已知的病因。副肿瘤性斯威特综合征占病例的15% - 20%,因此构成一个重要的亚组。有时其发病有助于怀疑潜在的恶性肿瘤,从而使及时干预成为可能。在本病例报告中,斯威特综合征是胆囊腺癌的首发特征;这种关联此前鲜有报道。