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儿童首次短时间(少于30分钟)热性惊厥后脑脊液酸碱状态及乳酸和丙酮酸浓度

Cerebrospinal fluid acid-base status and lactate and pyruvate concentrations after short (less than 30 minutes) first febrile convulsions in children.

作者信息

Simpson H, Habel A H, George E L

出版信息

Arch Dis Child. 1977 Nov;52(11):836-43. doi: 10.1136/adc.52.11.836.

Abstract

Twenty-nine infants and children with short (less than 30 minutes) first febrile convulsions were studied between 3 and 22 hours after convulsive episodes. Arterial and CSF acid-base variables, lactate and pyruvate concentrations, and lactate/pyruvate ratios were measured. Biochemical signs of cerebral hypoxia were found in only 2 patients, one of whom had short, repeated convulsions. Our findings indicate that hypoxic damage is unlikely to result from a short-duration febrile convulsion.

摘要

对29名首次热性惊厥持续时间较短(少于30分钟)的婴幼儿在惊厥发作后3至22小时进行了研究。测量了动脉血和脑脊液的酸碱变量、乳酸和丙酮酸浓度以及乳酸/丙酮酸比值。仅在2名患者中发现了脑缺氧的生化迹象,其中1名患者有短暂的反复惊厥。我们的研究结果表明,短时间的热性惊厥不太可能导致缺氧性损伤。

相似文献

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CSF acid-base changes after convulsions.惊厥后脑脊液酸碱变化。
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The CSF lactate-pyruvate ratio in cerebral hypoxia.
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本文引用的文献

6
Effects of convulsants on energy reserves in the cerebral cortex.惊厥剂对大脑皮层能量储备的影响。
J Neurochem. 1967 Jun;14(6):599-611. doi: 10.1111/j.1471-4159.1967.tb09563.x.
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Independence of blood and cerebrospinal fluid lactate.血液与脑脊液乳酸的独立性。
Arch Neurol. 1967 May;16(5):492-6. doi: 10.1001/archneur.1967.00470230044005.
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Blood gas calculator.血气计算器。
J Appl Physiol. 1966 May;21(3):1108-16. doi: 10.1152/jappl.1966.21.3.1108.
10
Acid-base changes in cerebrospinal fluid of infants with metabolic acidosis.
N Engl J Med. 1966 Mar 31;274(13):719-21. doi: 10.1056/NEJM196603312741306.

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