不同发作时长和病因的儿童惊厥后脑脊液酸碱状态及乳酸和丙酮酸浓度
Cerebrospinal fluid acid-base status and lactate and pyruvate concentrations after convulsions of varied duration and aetiology in children.
作者信息
Simpson H, Habel A H, George E L
出版信息
Arch Dis Child. 1977 Nov;52(11):844-9. doi: 10.1136/adc.52.11.844.
Abstract
Twenty-two infants and children were studied after convulsions of varied cause and duration. Arterial and CSF acid-base variables, lactate and pyruvate concentrations, and lactate/pyruvate ratios were measured between 3 and 18 hours after convulsive episodes. Biochemical signs of cerebral hypoxia were found in 7 patients with prolonged (greater than 30 minutes) or recurrent short convulsions. These signs were absent in patients with single short convulsions. These findings indicate that cerebral hypoxia and possible brain damage is a hazard of prolonged or rapidly recurring short convulsions.
摘要
对22名因各种原因和持续时间发生惊厥的婴幼儿进行了研究。在惊厥发作后3至18小时内测量动脉血和脑脊液的酸碱变量、乳酸和丙酮酸浓度以及乳酸/丙酮酸比值。在7例惊厥持续时间较长（超过30分钟）或反复短时间惊厥的患者中发现了脑缺氧的生化迹象。单次短时间惊厥的患者未出现这些迹象。这些发现表明，脑缺氧以及可能的脑损伤是长时间或快速反复短时间惊厥的一种危害。
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