Koren Gideon
The Motherisk Program, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, ON, Canada.
J Popul Ther Clin Pharmacol. 2012;19(3):e369-70. Epub 2012 Oct 11.
Recent studies have powerfully demonstrated that women with depression, whether treated with SSRIs or skip treatment, report double risk of cardiovascular malformations. Yet, physicians and epidemiologists continue to terrify women who are at serious life threatening risks if not treated pharmacologically, with non evidence-based information. This paper calls for immediate stop of such practice.
最近的研究有力地表明,患有抑郁症的女性,无论是否接受选择性5-羟色胺再摄取抑制剂(SSRI)治疗或未接受治疗,出现心血管畸形的风险都会加倍。然而,医生和流行病学家仍在用没有证据的信息吓唬那些如果不进行药物治疗就会面临严重生命威胁风险的女性。本文呼吁立即停止这种做法。