DeSimone Christopher V, DeSimone Daniel C, Hagler Donald J, Friedman Paul A, Asirvatham Samuel J
Department of Internal Medicine, Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
Pacing Clin Electrophysiol. 2013 Jan;36(1):50-4. doi: 10.1111/pace.12014. Epub 2012 Oct 18.
Implanted cardiac devices, including pacemakers, defibrillators, and resynchronization devices, are known to develop thrombus on their intravascular leads. Patent foramen ovale (PFO) occurs in approximately one-quarter of the adult population. It is unclear whether paradoxical cardioembolism and clinically relevant stroke occur in patients with implanted cardiac leads and PFO. We present a case series of four patients with cardioembolic stroke, presumed to arise from intravascular cardiac leads and associated PFO that required device closure of the PFO.
植入式心脏设备，包括起搏器、除颤器和再同步化设备，已知会在其血管内导线上形成血栓。卵圆孔未闭（PFO）在大约四分之一的成年人群中出现。目前尚不清楚在植入心脏导线和PFO的患者中是否会发生反常心脏栓塞和具有临床意义的中风。我们报告了一组4例心脏栓塞性中风患者的病例系列，推测这些中风源于血管内心脏导线并伴有PFO，这些患者需要通过封堵器封堵PFO。
