Park Seung, Pantanowitz Liron, Parwani Anil Vasdev
Division of Pathology Informatics, Department of Pathology, UPMC Shadyside Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA 15232, USA.
Clin Lab Med. 2012 Dec;32(4):557-84. doi: 10.1016/j.cll.2012.07.006.
Advances in computing speed and power have made a pure digital work flow for pathology. New technologies such as whole slide imaging (WSI), multispectral image analysis, and algorithmic image searching seem poised to fundamentally change the way in which pathology is practiced. This article provides the practicing pathologist with a primer on digital imaging. Building on this primer, the current state of the art concerning digital imaging in pathology is described. Emphasis is placed on WSI and its ramifications, showing how it is useful in both anatomic (histology, cytopathology) and clinical (hematopathology) pathology. Future trends are also extrapolated.
计算速度和能力的提升使得病理学领域拥有了纯粹的数字工作流程。诸如全切片成像(WSI)、多光谱图像分析和算法图像搜索等新技术似乎准备从根本上改变病理学的实践方式。本文为执业病理学家提供了一份数字成像入门指南。在此入门指南的基础上,描述了病理学中数字成像的当前技术水平。重点放在全切片成像及其影响方面,展示其在解剖学(组织学、细胞病理学)和临床(血液病理学)病理学中的作用。还推断了未来的发展趋势。