Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.
Department of Pathology, Ohio State University Wexner Medical Center, Columbus, OH.
Adv Anat Pathol. 2020 Jul;27(4):251-259. doi: 10.1097/PAP.0000000000000273.
Pathology has benefited from advanced innovation with novel technology to implement a digital solution. Whole slide imaging is a disruptive technology where glass slides are scanned to produce digital images. There have been significant advances in whole slide scanning hardware and software that have allowed for ready access of whole slide images. The digital images, or whole slide images, can be viewed comparable to glass slides in a microscope, as digital files. Whole slide imaging has increased in adoption among pathologists, pathology departments, and scientists for clinical, educational, and research initiatives. Worldwide usage of whole slide imaging has grown significantly. Pathology regulatory organizations (ie, College of American Pathologists) have put forth guidelines for clinical validation, and the US Food and Drug Administration have also approved whole slide imaging for primary diagnosis. This article will review the digital pathology ecosystem and discuss clinical and nonclinical applications of its use.
病理学受益于先进的创新技术，实现了数字化解决方案。全玻片成像技术是一种具有颠覆性的技术，它可以对载玻片进行扫描，生成数字图像。全玻片扫描硬件和软件取得了重大进展，使人们可以方便地访问全玻片图像。这些数字图像，或全玻片图像，可以以数字文件的形式，在显微镜下与玻璃载玻片进行类似的查看。全玻片成像技术在病理学家、病理科和科学家中越来越多地被用于临床、教育和研究活动。全球范围内全玻片成像的使用显著增加。病理学监管组织（例如美国病理学家协会）已经提出了临床验证指南，美国食品和药物管理局也已经批准全玻片成像用于初步诊断。本文将综述数字病理学的生态系统，并讨论其临床和非临床应用。
