Drakos Nicholas, Gausche-Hill Marianne
Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.
J Emerg Med. 2013 Mar;44(3):e291-4. doi: 10.1016/j.jemermed.2012.07.075. Epub 2012 Oct 15.
Paget-Schroetter syndrome (PSS) is a rare presentation of primary axillary subclavian vein thrombosis that classically occurs in young men with a degree of underlying thoracic outlet syndrome after a period of upper extremity exertion. The primary complication of PSS is post-thrombotic syndrome, a result of chronic venous hypertension.
To educate Emergency Physicians on this condition to potentiate timely diagnosis and appropriate disposition.
A 29-year-old right-handed restaurant waiter presented with 3 days of non-painful, gradual-onset right upper extremity swelling with normal vital signs. The patient's history was otherwise notable for subjective fevers and a right forearm abrasion. Upon examination, the right upper extremity was neurovascularly intact and remarkable for uniform edema and erythema extending distally from the level of the mid-humerus. The primary differential diagnoses were deep venous thrombosis (DVT) vs. soft tissue infection. Venous phase contrast computed tomography did not reveal evidence of underlying soft tissue infection and was inconclusive regarding a DVT. Ultrasound demonstrated a right subclavian vein DVT. The patient was admitted and underwent thrombolysis, venolysis, and first rib resection and initiation of warfarin.
PSS is a rare presentation of upper-extremity DVT occurring classically in patients without commonly recognized pro-thrombotic risk factors. PSS carries the potential of significant morbidity in the form of post-thrombotic syndrome and pulmonary embolism. Current literature suggests that optimal outcomes are achieved when treatment is initiated within 6 weeks of onset. The treatment paradigm calls for thrombolysis and, frequently, a first rib resection.
佩吉特-施罗特综合征(PSS)是原发性腋锁骨下静脉血栓形成的一种罕见表现,典型地发生于有一定程度胸廓出口综合征的年轻男性,常在一段时间的上肢用力之后。PSS的主要并发症是血栓形成后综合征,这是慢性静脉高压的结果。
对急诊医生进行关于这种疾病的教育,以促进及时诊断和恰当处置。
一名29岁惯用右手的餐厅服务员,出现右侧上肢无痛性、渐进性肿胀3天,生命体征正常。患者病史中值得注意的是有主观发热和右前臂擦伤。检查时,右侧上肢神经血管完好,显著表现为从中肱骨水平向远端延伸的均匀水肿和红斑。主要鉴别诊断为深静脉血栓形成(DVT)与软组织感染。静脉期对比计算机断层扫描未显示潜在软组织感染的证据,对于DVT的诊断不明确。超声显示右侧锁骨下静脉DVT。患者入院,接受了溶栓、静脉溶解、第一肋切除术并开始使用华法林。
PSS是上肢DVT的一种罕见表现,典型地发生于无常见公认血栓形成危险因素的患者。PSS有以血栓形成后综合征和肺栓塞形式出现的显著发病风险。当前文献表明,在发病6周内开始治疗可取得最佳结果。治疗模式要求进行溶栓,并且常常进行第一肋切除术。