射频消融和乙醇消融治疗复发性甲状腺癌：现状与挑战。
Radiofrequency and ethanol ablation for the treatment of recurrent thyroid cancers: current status and challenges.
机构信息
Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-Gu, Seoul, Korea.
出版信息
Curr Opin Oncol. 2013 Jan;25(1):14-9. doi: 10.1097/CCO.0b013e32835a583d.
PURPOSE OF REVIEW
To review the role and safety of radiofrequency ablation (RFA) and ethanol ablation for the treatment of recurrent thyroid cancers in patients at high risk of surgery.
RECENT FINDINGS
RFA and ethanol ablation are currently used as local tumor control methods for the treatment of recurrent thyroid cancers. The therapeutic success rates of RFA and ethanol ablation have been reported to be 75-91.6 and 70.8-98%, respectively. Local tumor recurrence has been reported to be 0-25% following RFA and 3.2-33% following ethanol ablation. Various complications have also been reported, such as discomfort, pain, skin burning, and changes in voice, but not life-threatening complications. All patients with changes in their voice received treatment to the central neck area, and permanent injury has been reported in patients who received RFA.
SUMMARY
RFA and ethanol ablation could be considered as nonsurgical treatment options for recurrent thyroid cancers in patients at high risk of surgery. Efficacy seems to be higher for RFA, but complications seem to be lower for ethanol ablation.
目的综述
探讨射频消融（RFA）和乙醇消融术在高手术风险的复发性甲状腺癌患者中的作用和安全性。
最近的发现
RFA 和乙醇消融术目前被用作复发性甲状腺癌的局部肿瘤控制方法。RFA 和乙醇消融术的治疗成功率分别为 75-91.6%和 70.8-98%。RFA 后局部肿瘤复发率为 0-25%，乙醇消融后为 3.2-33%。还报道了各种并发症，如不适、疼痛、皮肤灼伤和声音变化，但无危及生命的并发症。所有声音改变的患者均接受了中央颈部区域的治疗，RFA 治疗的患者有报道出现永久性损伤。
总结
RFA 和乙醇消融术可作为高手术风险的复发性甲状腺癌患者的非手术治疗选择。RFA 的疗效似乎更高，但乙醇消融术的并发症似乎更低。
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