Oswald S G, Van Nostrand D, Savory C G, Anderson J H, Callaghan J J
Nuclear Medicine Service, Walter Reed Army Medical Center, Washington, D.C.
J Nucl Med. 1990 Mar;31(3):274-80.
Although few studies address the use of three-phase bone scanning (TPBS) and indium-111-labeled white blood cell scintigraphy (111In-WBC) in hip arthroplasty utilizing a porous-coated prosthesis, the literature suggests that scintigraphic patterns in the uncomplicated patient may differ form that seen with the cemented prosthesis. In an attempt to determine the scintigraphic natural history, 25 uncomplicated porous-coated hip arthroplasties in 21 patients were prospectively studied with serial TPBS and 111In-WBC at approximately 7 days, and 3, 6, 12, 18, and 24 mo postoperatively. This report deals with findings related to the acetabulum. All 25 prostheses (144 of 144 scans) demonstrated increased uptake on the bone-phase images. Although this activity decreased with time, 76% had persistent uptake at 24 mo. Twenty-three of 25 prostheses (126 of 140 scans) showed increased uptake on 111In-WBC scintigraphy, invariably decreasing with time, but with 37% having significant uptake at 24 mo. Scintigraphic patterns in the uncomplicated porous-coated hip arthroplasty patient appear to differ from patterns described in cemented prostheses.
虽然很少有研究涉及三相骨扫描（TPBS）和铟-111标记的白细胞闪烁扫描（111In-WBC）在使用多孔涂层假体的髋关节置换术中的应用，但文献表明，无并发症患者的闪烁扫描模式可能与骨水泥假体的情况不同。为了确定闪烁扫描的自然病程，对21例患者的25例无并发症的多孔涂层髋关节置换术进行了前瞻性研究，在术后约7天以及3、6、12、18和24个月时进行了系列TPBS和111In-WBC检查。本报告涉及与髋臼相关的研究结果。所有25个假体（144次扫描中的144个）在骨相图像上均显示摄取增加。虽然这种活性随时间降低，但76%在24个月时仍有持续摄取。25个假体中的23个（140次扫描中的126个）在111In-WBC闪烁扫描中显示摄取增加，摄取量总是随时间减少，但37%在24个月时仍有明显摄取。无并发症的多孔涂层髋关节置换术患者的闪烁扫描模式似乎与骨水泥假体中描述的模式不同。
