Society for Reproductive Medicine and Society for Assisted Reproductive Technology, Birmingham, Alabama.
Fertil Steril. 2013 Jan;99(1):37-43. doi: 10.1016/j.fertnstert.2012.09.028. Epub 2012 Oct 22.
There is good evidence that fertilization and pregnancy rates are similar to IVF/ICSI with fresh oocytes when vitrified/warmed oocytes are used as part of IVF/ICSI for young women. Although data are limited, no increase in chromosomal abnormalities, birth defects, and developmental deficits has been reported in the offspring born from cryopreserved oocytes when compared to pregnancies from conventional IVF/ICSI and the general population. Evidence indicates that oocyte vitrification and warming should no longer be considered experimental. This document replaces the document last published in 2008 titled, "Ovarian Tissue and Oocyte Cryopreservation," Fertil Steril 2008;90:S241-6.
有充分的证据表明,在使用冷冻/解冻卵子作为年轻女性 IVF/ICSI 的一部分时,受精率和妊娠率与新鲜卵子的 IVF/ICSI 相似。尽管数据有限,但与传统 IVF/ICSI 和普通人群相比,从冷冻卵子中出生的后代并没有报告染色体异常、出生缺陷和发育缺陷的增加。有证据表明,卵子的玻璃化和解冻不应再被视为实验性的。本文件取代了 2008 年发表的题为“卵巢组织和卵母细胞冷冻保存”的文件,Fertil Steril 2008;90:S241-6。