Tang I P, Singh S, Krishnan G, Looi L M
Otorhinolaryngology Department, Faculty of Medicine, University of Malaysia, Sarawak, Malaysia.
J Laryngol Otol. 2012 Dec;126(12):1284-6. doi: 10.1017/S0022215112002435. Epub 2012 Oct 19.
We report a rare case of small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses with intracranial extension, and discuss the management of this rare tumour.
Small cell neuroendocrine carcinoma involving the nasal cavity and paranasal sinuses with intracranial extension may be treated successfully with surgery alone, without development of local recurrence.
Small cell neuroendocrine carcinoma is a locally aggressive tumour with a high rate of recurrence. Early and aggressive surgical excision with or without radiotherapy or chemotherapy can improve a patient's outcome and prognosis. Regular follow up is needed to detect any local or distant recurrence.
我们报告一例罕见的鼻腔和鼻窦小细胞神经内分泌癌伴颅内侵犯病例,并讨论这种罕见肿瘤的治疗方法。
累及鼻腔和鼻窦并伴有颅内侵犯的小细胞神经内分泌癌,单纯手术治疗可能成功,且无局部复发。
小细胞神经内分泌癌是一种具有高复发率的局部侵袭性肿瘤。早期积极的手术切除联合或不联合放疗或化疗可改善患者的治疗效果和预后。需要定期随访以发现任何局部或远处复发。