Remacle M, Bertrand B, Eloy P, Marbaix E
Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital of Mont-Godinne, Louvain University, Yvoir, Belgium.
Laryngoscope. 1990 Mar;100(3):269-74. doi: 10.1288/00005537-199003000-00011.
The use of Gax collagen is proposed for correcting velopharyngeal insufficiency with posterior pharyngeal wall augmentation. The indications for this procedure are velopharyngeal insufficiency that remains after surgery and treatment by a speech pathologist. The procedure is also valuable after velum paralysis. Collagen (2.5-5cc) is injected through a device designed for vocal-fold and laryngeal rehabilitation. Several injection points are necessary to raise a good Passavant's ridge. The muscular activity of the posterior pharyngeal wall models the collagen pad for the first 3 weeks; afterwards, the collagen shape remains unchanged due to its integration in the host tissues. At this time, five patients have been injected with Gax collagen and have improved. The oldest case dates from 28 months ago; the most recent dates from 8 months ago. There were no adverse reactions, and the results remain stable at the present time.
有人提出使用Gax胶原蛋白通过咽后壁增厚来纠正腭咽功能不全。该手术的适应症是手术后及言语病理学家治疗后仍存在的腭咽功能不全。在腭帆麻痹后该手术也很有价值。通过一种为声带和喉部康复设计的装置注射胶原蛋白（2.5 - 5立方厘米）。需要几个注射点来形成一个良好的帕萨万特嵴。咽后壁的肌肉活动在最初3周塑造胶原蛋白垫；之后，由于其整合到宿主组织中，胶原蛋白形状保持不变。目前，已有5名患者注射了Gax胶原蛋白并有所改善。最早的病例发生在28个月前；最近的病例发生在8个月前。没有不良反应，目前结果保持稳定。
