Furlow L T, Williams W N, Eisenbach C R, Bzoch K R
Cleft Palate J. 1982 Jan;19(1):47-56.
Thirty-five individuals with velopharyngeal insufficiency, including eight with failed pharyngeal flaps, were treated with injectable Teflon and followed postoperatively for an average of three years. The patients' speech and voice quality were evaluated pre- and postoperatively, and an outcome was judged successful only if there was total elimination of the preoperative symptoms of hypernasality and inappropriate nasal air emission. All patients were evaluated preoperatively with cinefluorography, and an attempt was made to obtain serial postoperative films in order to determine the stability of the Teflon pad with time. An overall success rate of 74% was achieved. Success for patients with VPI, excluding those patients with pharyngeal flaps was 78%. In treating the failed pharyngeal flap cases we achieved a 62% success rate. The stability of the implanted Teflon was assessed over time as determined from measurements made on patients who received two or more postoperative cine films. Statistical analysis revealed no significant change in thickness of the pad over a period of time. Our conclusions are that with careful case selection, the injectable Teflon procedure is safe, effective and that the implant remains stable with time.
35例腭咽闭合不全患者，其中8例咽瓣手术失败，接受了可注射特氟龙治疗，术后平均随访3年。对患者术前和术后的语音和嗓音质量进行评估，只有在术前高鼻音和不当鼻漏气症状完全消除的情况下，治疗结果才判定为成功。所有患者术前均进行了动态荧光造影评估，并尝试获取术后系列影像，以确定特氟龙垫随时间的稳定性。总体成功率为74%。排除咽瓣手术患者，腭咽闭合不全患者的成功率为78%。在治疗咽瓣手术失败病例时，我们取得了62%的成功率。通过对接受了两张或更多术后动态荧光造影影像的患者进行测量，评估植入特氟龙随时间的稳定性。统计分析显示，一段时间内垫的厚度没有显著变化。我们的结论是，经过仔细的病例选择，可注射特氟龙手术是安全、有效的，并且植入物随时间保持稳定。
