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术前输尿管支架置入对输尿管镜治疗肾输尿管结石结石清除率的影响:286 例配对分析。

Impact of preoperative ureteral stenting on stone-free rates of ureteroscopy for nephroureterolithiasis: a matched-paired analysis of 286 patients.

机构信息

Department of Urology, Asklepios Hospital Barmbek, Hamburg, Germany.

出版信息

Urology. 2012 Dec;80(6):1214-9. doi: 10.1016/j.urology.2012.06.064. Epub 2012 Oct 18.

Abstract

OBJECTIVE

To determine the effect of preoperative ureteral stenting on success rates of ureteroscopy (URS) for nephroureterolithiasis.

MATERIALS AND METHODS

We retrospectively evaluated patients who underwent URS for nephroureterolithiasis without preoperative indwelling ureteral stents. These patients were matched according to age, sex, body mass index, and stone side, size, site, and number of stones per patient, with patients who had been prestented before URS. Patient data, stone-free rates (SFRs), and complications were compared.

RESULTS

The study included 286 patients (143 stented vs 143 nonstented). The mean stone size was 5.69 ± 3 mm. The mean number of stones per patient was 1.35 ± 0.7. The overall SFR after 1 URS procedure was 90.9% and higher in prestented than in nonstented patients (95.1% vs 86.7%, P ≤ .013). For ureteral stones, the SFR was 99% in prestented and 90% in nonstented patients (P ≤ .0048). The SFR did not differ between the groups for ureteral stones <5 mm, but was higher in prestented than in nonstented patients for ureteral calculi ≥ 5 mm (98.2% vs 83.3%, P ≤ .0105). For urinary calculi ≥ 5 mm, the overall SFR was higher in prestented than in nonstented patients (93.3 vs 78.3%, P ≤ .0054). Perioperative complications occurred in 27 patients (9.4%; Clavien I, 6.6%; Clavien IIIb, 2.8%) without differences between the groups.

CONCLUSION

URS is a safe and efficacious procedure for the treatment of nephroureterolithiasis. Preoperative ureteral stent placement is associated with higher SFRs compared with nonstented patients for urinary calculi ≥ 5 mm. Nonstented patients with urinary calculi ≥ 5 mm should be informed about the risk for a second-look URS procedure.

摘要

目的

确定术前输尿管支架置入对输尿管镜碎石术(URS)治疗肾盂输尿管结石的成功率的影响。

材料与方法

我们回顾性评估了未行术前留置输尿管支架的肾盂输尿管结石行 URS 治疗的患者。根据年龄、性别、体重指数以及结石侧别、大小、部位和每位患者的结石数量,将这些患者与行 URS 前留置输尿管支架的患者进行匹配。比较患者资料、无结石率(SFR)和并发症。

结果

研究共纳入 286 例患者(143 例有支架置入,143 例无支架置入)。平均结石大小为 5.69±3mm。每位患者的平均结石数量为 1.35±0.7 枚。单次 URS 术后总体 SFR 为 90.9%,支架置入组高于无支架置入组(95.1%比 86.7%,P≤0.013)。对于输尿管结石,支架置入组的 SFR 为 99%,无支架置入组为 90%(P≤0.0048)。对于<5mm 的输尿管结石,两组间 SFR 无差异,但对于≥5mm 的输尿管结石,支架置入组高于无支架置入组(98.2%比 83.3%,P≤0.0105)。对于≥5mm 的尿路结石,支架置入组的总体 SFR 高于无支架置入组(93.3%比 78.3%,P≤0.0054)。27 例(9.4%)患者发生围手术期并发症(Clavien I 级 6.6%,Clavien IIIb 级 2.8%),两组间无差异。

结论

URS 是治疗肾盂输尿管结石的一种安全有效的方法。与无支架置入患者相比,术前输尿管支架置入可提高≥5mm 尿路结石的 SFR。对于≥5mm 的尿路结石患者,如果不置入支架,应告知其行二次 URS 检查的风险。

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