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戈谢病综合征患者的麻醉考量:一例病例报告及文献综述

Anaesthetic consideration in patients with Gorham's syndrome: A case report and review of the literature.

作者信息

Sahoo Rajendra Kumar, Jagannathan Balavenkatasubramanian, Palanichamy Gurumoorthi, Natarajan Vivekanand

机构信息

Department of Anaesthesiology, Ganga Medical Centre and Hospital, Coimbatore, Tamil Nadu, India.

出版信息

Indian J Anaesth. 2012 Jul;56(4):391-3. doi: 10.4103/0019-5049.100831.

Abstract

Gorham's syndrome (GS) is a rare disorder characterized by proliferation of vascular channels resulting in destruction and resorption of osseous matrix leading to bone loss. Bone loss leads to joint instability and problems during airway management and positioning for surgery. Respiratory involvement further complicates anaesthesia management. We report the anaesthetic care of a 21-year-old male patient of known GS for spine decompression and fusion in prone position. Airway management, induction technique, pathophysiology of the disease, drug selection and other concerns of anaesthesia for major spine surgery has been discussed reviewing the sparse literature available.

摘要

戈勒姆综合征(GS)是一种罕见的疾病,其特征是血管通道增生,导致骨基质破坏和吸收,进而导致骨质流失。骨质流失会导致关节不稳定,并在气道管理和手术体位摆放过程中引发问题。呼吸系统受累使麻醉管理更加复杂。我们报告了一例已知患有戈勒姆综合征的21岁男性患者在俯卧位下行脊柱减压融合术的麻醉处理情况。通过回顾现有的少量文献,讨论了气道管理、诱导技术、该疾病的病理生理学、药物选择以及大型脊柱手术麻醉的其他相关问题。

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本文引用的文献

1
Anesthetic management of a pregnant woman with Gorham-Stout disease.孕妇戈勒姆-斯图特病的麻醉管理。
Int J Obstet Anesth. 2011 Jan;20(1):85-8. doi: 10.1016/j.ijoa.2010.09.007. Epub 2010 Dec 15.
3
Gorham's disease or massive osteolysis.戈谢病或大块骨质溶解症。
Clin Med Res. 2005 May;3(2):65-74. doi: 10.3121/cmr.3.2.65.
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Anesthesia for a patient with Gorham's syndrome: "disappearing bone disease".
Anesthesiology. 1994 Feb;80(2):466-8. doi: 10.1097/00000542-199402000-00027.

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