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唑来膦酸:戈谢病的治疗选择。 (注:原文中疾病名称有误,戈谢病英文是Gaucher disease ,这里原文说的Gorham-Stout disease是骨消失症,也叫大块骨质溶解症 ,译文按正确疾病名称翻译了,但按原文错误名称的话应是:唑来膦酸:骨消失症的治疗选择 )

Zoledronic acid : Treatment option for Gorham-Stout disease.

作者信息

Illeez Ozge Gulsum, Ozkan Korhan, Ozkan Feyza Unlu, Bostan Ali Burak, Akpinar Fuat, Bilgic Bilge, Aktas Ilknur

机构信息

Fatih Sultan Mehmet Training and Research Hospital, Department of Physical Medicine and Rehabilitation, University of Health Sciences, 34752, Istanbul, Turkey.

Faculty of Medicine, Göztepe Training and Research Hospital, Department of Orthopaedics and Traumatology, Istanbul Medeniyet University, 34722, Istanbul, Turkey.

出版信息

Orthopade. 2018 Dec;47(12):1032-1035. doi: 10.1007/s00132-018-3655-z.

Abstract

Gorham-Stout disease is a rare bone resorption disease, the etiology and prognosis of which is uncertain but it is thought to be benign. It can involve one or more bones and can cause pain, swelling, deformity and fractures in affected bones. Diagnosis is made with a combination of clinical, radiological and histopathological examinations once other causes of osteolysis have been excluded. Due to its rarity, there is no standard therapeutic approach.

摘要

戈勒姆-斯托特病是一种罕见的骨质吸收疾病,其病因和预后尚不确定,但被认为是良性的。它可累及一根或多根骨骼,并可导致受累骨骼出现疼痛、肿胀、畸形和骨折。一旦排除了其他骨质溶解原因,可通过临床、放射学和组织病理学检查相结合来进行诊断。由于其罕见性,目前尚无标准的治疗方法。

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