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2型糖尿病及其相关并发症的口腔表现。

Oral manifestations in type-2 diabetes and related complications.

作者信息

Bajaj Sarita, Prasad Suresh, Gupta Arvind, Singh Vijay Bahadur

机构信息

Department of Medicine, MLN Medical College, Allahabad, Uttar Pradesh, India.

出版信息

Indian J Endocrinol Metab. 2012 Sep;16(5):777-9. doi: 10.4103/2230-8210.100673.

Abstract

BACKGROUND

Knowledge of the wide spectrum of the oral markers of diabetes is imperative as one frequently encounters individuals with undetected, untreated or poorly controlled diabetes.

OBJECTIVES

The objective was to study the oral manifestations in type 2 diabetes mellitus (DM) and to establish an association between oral manifestations and associated microvascular and macrovascular complications.

MATERIALS AND METHODS

50 cases of DM were selected who had oral complications. The control group comprised 50 age- and sex-matched diabetic patients without any oral complications.

RESULTS

Oral manifestations in DM included periodontal disease in 34%, oral candidiasis in 24%, tooth loss in 24%, oral mucosal ulcers in 22%, taste impairment in 20%, xerostomia and salivary gland hypofunction in 14%, dental caries in 24%, and burning mouth sensation in 10% cases. Fasting [(FBG) (P = 0.003)] and postprandial blood glucose [(PPBG) (P = 0.0003)] levels were significantly higher among cases. The P values for neuropathy, retinopathy, nephropathy, cardiovascular disease, dyslipidemia, and sepsis were 0.0156, 0.0241, 0.68, 0.4047, 0.0278, and 0.3149, respectively, which were significant for neuropathy, retinopathy, and dyslipidemia.

CONCLUSIONS

Several oral complications are seen among diabetics. Association of oral markers in DM and microvascular complications suggests that there is a significant association between the two.

摘要

背景

由于经常遇到未被发现、未接受治疗或控制不佳的糖尿病患者,了解糖尿病广泛的口腔标志物知识至关重要。

目的

研究2型糖尿病(DM)的口腔表现,并建立口腔表现与相关微血管和大血管并发症之间的关联。

材料与方法

选取50例有口腔并发症的糖尿病患者。对照组由50例年龄和性别匹配、无任何口腔并发症的糖尿病患者组成。

结果

糖尿病患者的口腔表现包括:34%患牙周病,24%患口腔念珠菌病,24%牙齿缺失,22%患口腔黏膜溃疡,20%味觉障碍,14%口干和唾液腺功能减退,24%患龋齿,10%有灼口感。病例组的空腹血糖[(FBG)(P = 0.003)]和餐后血糖[(PPBG)(P = 0.0003)]水平显著更高。神经病变、视网膜病变、肾病、心血管疾病、血脂异常和败血症的P值分别为0.0156、0.0241、0.68、0.4047、0.0278和0.3149,其中神经病变、视网膜病变和血脂异常的P值具有统计学意义。

结论

糖尿病患者中可见多种口腔并发症。糖尿病的口腔标志物与微血管并发症之间的关联表明两者之间存在显著关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/586e/3475903/6d1e07e38097/IJEM-16-777-g003.jpg

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