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希腊克里特岛学龄前儿童的动脉粥样硬化风险因素。

Atherogenic risk factors among preschool children in Crete, Greece.

作者信息

Hatzis Christos M, Papandreou Christopher, Vardavas Constantine I, Athanasopoulos Dimitris, Balomenaki Euaggelia, Kafatos Anthony G

机构信息

Department of Social Medicine, Preventive Medicine and Nutrition Clinic, Medical School, University of Crete, P.O. Box 1393 Heraklion, Crete, Greece.

出版信息

Indian J Endocrinol Metab. 2012 Sep;16(5):809-14. doi: 10.4103/2230-8210.100683.

Abstract

OBJECTIVE

To investigate the presence of atherogenic factors among preschool children of Crete, Greece.

MATERIALS AND METHODS

This was a cross-sectional study. The study population included 1189 children, aged four to seven years, examined from January to May 2005, in public kindergartens. Biochemical, anthropometric, and blood pressure measurements were performed.

RESULTS

Of the boys 27.4% were classified as overweight or obese (obese 10.8%). The respective percentage for girls was 28.5% (obese 9%); 7.4% percent of the boys and 7.9% of the girls had blood pressure above the ninety-fifth percentile. TC of > 200 mg / dl was found in 14.4% and LDL-C of > 130 mg / dl in 13.8% of the children. Children with serum TG of > 100 mg / dl had a significantly higher mean WC and BMI than those with triglyceride levels of ≤ 80 mg / dl (59.7 vs. 55.9 cm and 17.9 vs. 16.6 kg / m(2); P < 0.05). Similarly, children with HDL-C < 45 mg / dl had significantly higher WC and BMI than children with HDL-C ≥ 60 mg / dl (57.7 vs. 53.5 cm and 17.1 vs. 16.5 kg / m(2); P < 0.05). Obese children had an Odds Ratio of 2.87 (95% confidence interval, 1.05 - 7.85, P = 0.041) for hypertriglyceridemia, as compared to non-obese children.

CONCLUSION

Levels of obesity and especially central obesity were strongly related to other atherogenic risk factors in Cretan preschool children indicating the presence of this major public health problem in early ages.

摘要

目的

调查希腊克里特岛学龄前儿童中致动脉粥样硬化因素的存在情况。

材料与方法

这是一项横断面研究。研究人群包括1189名4至7岁的儿童,于2005年1月至5月在公立幼儿园接受检查。进行了生化、人体测量和血压测量。

结果

男孩中有27.4%被归类为超重或肥胖(肥胖占10.8%)。女孩的相应百分比为28.5%(肥胖占9%);7.4%的男孩和7.9%的女孩血压高于第95百分位数。14.4%的儿童总胆固醇>200mg/dl,13.8%的儿童低密度脂蛋白胆固醇>130mg/dl。血清甘油三酯>100mg/dl的儿童平均腰围和体重指数显著高于甘油三酯水平≤80mg/dl的儿童(59.7对55.9cm,17.9对16.6kg/m²;P<0.05)。同样,高密度脂蛋白胆固醇<45mg/dl的儿童腰围和体重指数显著高于高密度脂蛋白胆固醇≥60mg/dl的儿童(57.7对53.5cm,17.1对16.5kg/m²;P<0.05)。与非肥胖儿童相比,肥胖儿童患高甘油三酯血症的优势比为2.87(95%置信区间,1.05 - 7.85,P = 0.041)。

结论

肥胖水平,尤其是中心性肥胖,与克里特岛学龄前儿童的其他致动脉粥样硬化危险因素密切相关,表明这一主要公共卫生问题在早年就已存在。

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