Abrahmsohn G M, Halberstein R A, Fregeolle S
International Institute of Nutrition and Stress, Dental Connection, Key Biscayne, Florida, USA.
Gen Dent. 1993 Nov-Dec;41(6):523-7; quiz 529-30.
The present study augments a growing body of evidence that indicates supplemental vitamin C may be beneficial in speeding healing following tooth extraction and in reducing the likelihood of alveolalgia and other complications. No adverse side effects were encountered from administration of vitamin C in our studies or in a recent investigation involving intake of 10 g/day; thus, carefully tested higher dosages ("megadose therapy") might be applied successfully to patients with alveolalgia or orthognathic conditions. Hanck comments on the relative safety of ascorbic acid in medicine: "The few literature references suggesting adverse effects of ascorbic acid are outnumbered by a large number of clinical studies in which no adverse effects have been observed. Up to 5 g of ascorbic acid daily may be administered safely even over a long-term". Further research is recommended to determine whether vitamin C is of similar value in hastening proper recovery from other oral surgical procedures. Vitamin C is a relatively safe, inexpensive, over-the-counter product that may be more effective in dental healing than previously known.
本研究进一步证明了越来越多的证据，表明补充维生素C可能有助于加快拔牙后的愈合速度，并降低干槽症和其他并发症的发生几率。在我们的研究以及最近一项涉及每日摄入10克维生素C的调查中，均未发现服用维生素C有任何不良副作用；因此，经过仔细测试的更高剂量（“大剂量疗法”）可能成功应用于患有干槽症或正颌疾病的患者。汉克评论了抗坏血酸在医学上的相对安全性：“少数文献提及抗坏血酸有不良影响，但大量临床研究均未观察到不良影响，数量远超前者。即使长期服用，每天安全服用量可达5克抗坏血酸”。建议进一步研究以确定维生素C在加速其他口腔外科手术的正常恢复方面是否具有类似价值。维生素C是一种相对安全、廉价的非处方产品，在牙齿愈合方面可能比之前认为的更有效。
