Khong P-L, Frush D, Ringertz H
Department of Diagnostic Radiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
Ann ICRP. 2012 Oct-Dec;41(3-4):170-8. doi: 10.1016/j.icrp.2012.06.017. Epub 2012 Sep 12.
It is well known that paediatric patients are generally at greater risk for the development of cancer per unit of radiation dose compared with adults, due both to the longer life expectancy for any harmful effects of radiation to manifest, and the fact that developing organs and tissues are more sensitive to the effects of radiation. Multiple computed tomography (CT) examinations may cumulatively involve absorbed doses to organs and tissues that can sometimes approach or exceed the levels known from epidemiological studies to significantly increase the probability of cancer development. Radiation protection strategies include rigorous justification of CT examinations and the use of imaging techniques that are non-ionising, followed by optimisation of radiation dose exposure (according to the 'as low as reasonably achievable' principle). Special consideration should be given to the availability of dose reduction technology when acquiring CT scanners. Dose reduction should be optimised by adjustment of scan parameters (such as mAs, kVp, and pitch) according to patient weight or age, region scanned, and study indication (e.g. images with greater noise should be accepted if they are of sufficient diagnostic quality). Other strategies include restricting multiphase examination protocols, avoiding overlapping of scan regions, and only scanning the area in question. Newer technologies such as tube current modulation, organ-based dose modulation, and iterative reconstruction should be used when appropriate. Attention should also be paid to optimising study quality (e.g. by image post-processing to facilitate radiological diagnoses and interpretation). Finally, improving awareness through education and advocacy, and further research in paediatric radiological protection are important to help reduce patient dose.
众所周知,与成人相比,儿科患者每单位辐射剂量患癌症的风险通常更高,这既是因为辐射的任何有害影响显现所需的预期寿命更长,也是因为发育中的器官和组织对辐射影响更敏感。多次计算机断层扫描(CT)检查可能会累积使器官和组织受到吸收剂量,有时这些剂量可能接近或超过流行病学研究中已知的会显著增加患癌概率的水平。辐射防护策略包括严格论证CT检查的必要性以及使用非电离成像技术,随后根据“尽可能合理达到最低水平”原则优化辐射剂量暴露。购置CT扫描仪时应特别考虑剂量降低技术的可用性。应根据患者体重或年龄、扫描部位以及研究指征(例如,如果具有足够的诊断质量,应接受噪声较大的图像)调整扫描参数(如管电流、管电压和螺距)来优化剂量降低。其他策略包括限制多期检查方案、避免扫描区域重叠以及仅扫描相关区域。应在适当的时候使用管电流调制、基于器官的剂量调制和迭代重建等新技术。还应注意优化研究质量(例如通过图像后处理以促进放射学诊断和解读)。最后,通过教育和宣传提高认识以及进一步开展儿科放射防护研究对于帮助降低患者剂量很重要。