Vidal Melo Marcos F, Musch Guido, Kaczka David W
Department of Anaesthesia, Harvard Medical School, Boston, MA 02215, USA.
Anesthesiol Clin. 2012 Dec;30(4):759-84. doi: 10.1016/j.anclin.2012.08.003. Epub 2012 Sep 1.
Anesthesia, surgical requirements, and patients' unique pathophysiology all combine to make the accumulated knowledge of respiratory physiology and lung mechanics vital in patient management. This article take a case-based approach to discuss how the complex interactions between anesthesia, surgery, and patient disease affect patient care with respect to pulmonary pathophysiology and clinical decision making. Two disparate scenarios are examined: a patient with chronic obstructive pulmonary disease undergoing a lung resection, and a patient with coronary artery disease undergoing cardiopulmonary bypass. The impacts of important concepts in pulmonary physiology and respiratory mechanics on clinical management decisions are discussed.
麻醉、手术需求以及患者独特的病理生理学共同作用,使得呼吸生理学和肺力学的累积知识在患者管理中至关重要。本文采用基于病例的方法,讨论麻醉、手术和患者疾病之间的复杂相互作用如何在肺部病理生理学和临床决策方面影响患者护理。研究了两种不同的情况:一名患有慢性阻塞性肺疾病的患者接受肺切除术,以及一名患有冠状动脉疾病的患者接受体外循环手术。讨论了肺生理学和呼吸力学中的重要概念对临床管理决策的影响。