Bureau of International Cooperation, Department of Health, Executive Yuan, Taipei City, Taiwan.
J Formos Med Assoc. 2012 Oct;111(10):567-71. doi: 10.1016/j.jfma.2011.06.010. Epub 2012 May 5.
BACKGROUND/PURPOSE: Controversy exists in the literature regarding whether dentists with multiple occupational exposures suffer from premature mortality. A cohort mortality study was conducted to evaluate the survival outcome and determine if potential exposure to harmful agents leads to premature mortality among dentists.
Using the Life Table Analysis System, we calculated standardized mortality ratios (SMRs) for a cohort of 11,700 dentists affiliated with the Taiwan Dental Association. These dentists were followed from 1985-2009. Reference rates were derived from cause-, gender-, and age-specific mortality rates of the general population of Taiwan and 18,664 Taiwanese internists, who were considered to be more socioeconomically proximal to dentists. A Cox proportional hazard model was also constructed to determine multiple risk factors associated with mortality.
Compared with the general population, dentists in Taiwan consistently demonstrated reduced from all-cause mortality. However, compared with internists, significant and excess mortality were observed in dentists for overall mortality (SMR=1.13; 95% confidence interval [CI]=1.00-1.26), drowning (SMR=6.62; 95% CI=2.15-15.45), and heart diseases (SMR=1.66; 95% CI=1.22-2.21). After adjusting for other risk factors, the Cox model showed an increased hazard ratio of 1.17 (95% CI=1.01-1.37) for dentists.
Taiwanese dentists demonstrated significant elevated SMRs for overall causes, drowning, and heart diseases. Careful precaution should be taken to reduce these trends. Future studies are also needed for in-depth exploration of the mechanisms regarding how professional stress and exposure contribute to the increased risk of mortality in Taiwanese dentists.
背景/目的:关于是否存在接触多种职业因素的牙医会过早死亡的争议,文献中仍存在争议。本队列死亡率研究旨在评估生存结果,并确定潜在的有害因素暴露是否会导致牙医过早死亡。
使用寿命表分析系统,我们计算了台湾牙医协会的 11700 名牙医队列的标准化死亡率比(SMR)。这些牙医从 1985 年至 2009 年被随访。参考率来自台湾普通人群的死因、性别和年龄特定死亡率,以及 18664 名被认为与牙医更接近社会经济地位的台湾内科医生。还构建了 Cox 比例风险模型来确定与死亡率相关的多个危险因素。
与普通人群相比,台湾的牙医始终表现出全因死亡率降低。然而,与内科医生相比,牙医的全因死亡率(SMR=1.13;95%置信区间[CI]=1.00-1.26)、溺水(SMR=6.62;95%CI=2.15-15.45)和心脏病(SMR=1.66;95%CI=1.22-2.21)的死亡率显著升高且存在超额死亡。在调整其他危险因素后,Cox 模型显示牙医的危险比增加了 1.17(95%CI=1.01-1.37)。
台湾牙医的全因、溺水和心脏病的 SMR 显著升高。应谨慎采取预防措施以降低这些趋势。还需要进一步的研究来深入探讨职业压力和暴露如何导致台湾牙医死亡率增加的机制。