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调查美国医学物理学家协会报告 204 号文件对儿科 CT 实施的基于体型的剂量估算。

Investigation of American Association of Physicists in Medicine Report 204 size-specific dose estimates for pediatric CT implementation.

机构信息

Department of Radiological Sciences, St Jude Children's Research Hospital, 262 Danny Thomas Pl, Memphis, TN 38139, USA.

出版信息

Radiology. 2012 Dec;265(3):832-40. doi: 10.1148/radiol.12120131. Epub 2012 Oct 23.

Abstract

PURPOSE

To compare five methodologies the American Association of Physicists in Medicine Report 204 used to calculate size-specific dose estimates (SSDEs) for pediatric computed tomography (CT).

MATERIALS AND METHODS

The institutional review board waived consent for this HIPAA-compliant retrospective study. The five SSDE methodologies were investigated for calculation variation based on volumetric CT dose index (CTDI), or CTDI(vol), of chest, abdominal, and pelvic CT. SSDE calculations were derived from a predominantly pediatric population of 186 patients retrospectively and consecutively analyzed from June through November 2011. Eighty (43%) of the 186 patients were female, and 106 (57%) were male. Mean patient age was 8.6 years ± 6.3 (standard deviation), the age range was 1 month to 28 years, and mean weight was 37.7 kg ± 33.1, with a range of 3.4-146.6 kg. SSDE conversion factors were derived from anteroposterior (AP) and lateral dimensions measured on the patient's CT radiograph. The measurements were either used independently, or as a summation, or to calculate the patient's effective diameter; additionally, SSDE was derived on the basis of the patient's age (International Commission on Radiation Units Report 74 data). SSDE conversion factors were applied to CTDI(vol) data that corrected for both 16- and 32-cm-diameter CTDI phantom measurements. SSDE data were summarized by using the patient's originally prescribed weight-based CT scanning protocols. Data were summarized by using descriptive statistics.

RESULTS

SSDEs derived from individual measurements varied 2%-12%. The combination of measurements (sum or effective diameter) varied 0.9%-2%. The age approach varied by an average of 2% (in the younger population [0-13 years]), but up to 44%, with an average of 18% (in the older population [14-18 years]). No SSDE correction was required for patients of varying size who weighed 36 kg or less when CTDI(vol) was measured by using a 16-cm CTDI phantom or for patients weighing 100-140 kg when CTDI(vol) was measured by using a 32-cm phantom. CTDI(vol) measured by using a 32-cm phantom in patients weighing between 36 and 100 kg and patients weighing more than 140 kg differed from SSDE by an average of 35%. An average difference of 1% was found between male and female SSDE-corrected values when the two sexes were compared within the same CT weight scanning categories.

CONCLUSION

The combination of AP and lateral measurements should be used to determine SSDE correction factors when possible. For pediatric patients, CTDI(vol) calculated with a 32-cm phantom requires SSDE conversion to more accurately estimate patient dose; CTDI(vol) calculated with a 16-cm phantom for pediatric patients weighing 36 kg or less does not require SSDE conversion.

摘要

目的

比较美国医学物理学家协会报告 204 号报告中用于计算儿科计算机断层扫描(CT)的体积剂量指数(CTDI)特异性剂量估计值(SSDE)的 5 种方法。

材料和方法

本 HIPAA 合规性回顾性研究获得机构审查委员会同意豁免同意。根据胸部、腹部和盆腔 CT 的 CTDI(vol),研究了这 5 种 SSDE 方法的计算差异。SSDE 计算是从 2011 年 6 月至 11 月间回顾性和连续分析的 186 名主要儿科患者中得出的。186 名患者中 80 名(43%)为女性,106 名(57%)为男性。平均患者年龄为 8.6 岁±6.3(标准差),年龄范围为 1 个月至 28 岁,平均体重为 37.7kg±33.1kg,范围为 3.4-146.6kg。SSDE 转换因子是从患者 CT 射线照相上的前后(AP)和侧部尺寸得出的。这些测量结果可以单独使用,也可以汇总使用,也可以计算患者的有效直径;此外,还可以根据患者的年龄(国际辐射单位委员会报告 74 号数据)来计算 SSDE。将 SSDE 转换因子应用于校正了 16cm 和 32cm 直径 CTDI 体模测量值的 CTDI(vol)数据。根据患者最初规定的体重 CT 扫描方案,使用描述性统计方法对 SSDE 数据进行总结。

结果

个体测量得出的 SSDE 差异为 2%-12%。测量结果的组合(总和或有效直径)差异为 0.9%-2%。年龄法的差异平均为 2%(在 0-13 岁的年轻人群中),但在 14-18 岁的年龄较大的人群中,差异可达 44%,平均为 18%。当使用 16cm CTDI 体模测量 CTDI(vol)时,体重为 36kg 或更轻的患者,或当使用 32cm 体模测量 CTDI(vol)时,体重为 100-140kg 的患者,无需进行 SSDE 校正。当使用 32cm 体模测量体重在 36kg 至 100kg 之间的患者和体重超过 140kg 的患者的 CTDI(vol)时,与 SSDE 的差异平均为 35%。当在相同 CT 体重扫描类别中比较男女时,发现男性和女性 SSDE 校正值之间存在 1%的平均差异。

结论

当可能时,应使用前后和侧部测量的组合来确定 SSDE 校正因子。对于儿科患者,使用 32cm 体模计算的 CTDI(vol)需要 SSDE 转换,以更准确地估计患者剂量;对于体重为 36kg 或更轻的儿科患者,使用 16cm 体模计算的 CTDI(vol)不需要 SSDE 转换。

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